You don't set PYTHONPATH, you add entries to sys.path. It's a list of directories that should be searched for Python packages, so you can just append your directories to that list.

import sys

sys.path.append('/path/to/whatever')

In fact, sys.path is initialized by splitting the value of PYTHONPATH on the path separator character (: on Linux-like systems, ; on Windows).

You can also add directories using site.addsitedir, and that method will also take into account .pth files existing within the directories you pass. (That would not be the case with directories you specify in PYTHONPATH.)

The site module documentation and Modifying Python's Search Path seem to be what you're looking for.

As far as I understand it, those entries are being added to sys.path by:

• /usr/lib/python2.6/site.py
• /usr/lib/python2.6/dist-packages/site.py
  (Change 2.6 to your version of Python.)

The easiest way to change it is to add a file /usr/local/lib/python2.6/dist-packages/site-packages.pth containing ../site-packages.

Alternatively, maybe you can teach the package to use site.getsitepackages()?

Try appending to PYTHONPATH instead of overwriting it completely.

export PYTHONPATH=$PYTHONPATH:/home/dev/python-files

References:

According to the the Python documentation on PYTHONPATH

Augment the default search path for module files. [...]

The default search path is installation dependent, but generally begins with prefix/lib/pythonversion (see PYTHONHOME above). It is always appended to PYTHONPATH.

meaning that some values exist in PYTHONPATH and the default search path is also only appended.

Additionally, this blog post (Archive.org link) also explains clearly why you need to append to PYTHONPATH and not overwrite it. Scrolling down to the section - Special cases and examining the search path explains it clearly (unfortunately no relative URL to that link so you'll have to scroll). Although the user gives the examples on a mac they are very much relevant to any platform

You don't have to set either of them. PYTHONPATH can be set to point to additional directories with private libraries in them. PYTHONHOME sets the location of default libraries.

Documentation:

PYTHONHOME
Change the location of the standard Python libraries. By default, the libraries are searched in prefix/lib/pythonversion and exec_prefix/lib/pythonversion, where prefix and exec_prefix are installation-dependent directories, both defaulting to /usr/local.

When PYTHONHOME is set to a single directory, its value replaces both prefix and exec_prefix. To specify different values for these, set PYTHONHOME to prefix:exec_prefix.

PYTHONPATH
Augment the default search path for module files. The format is the same as the shell’s PATH: one or more directory pathnames separated by os.pathsep (e.g. colons on Unix or semicolons on Windows). Non-existent directories are silently ignored.

In addition to normal directories, individual PYTHONPATH entries may refer to zipfiles containing pure Python modules (in either source or compiled form). Extension modules cannot be imported from zipfiles.

The default search path is installation dependent, but generally begins with prefix/lib/pythonversion (see PYTHONHOME above). It is always appended to PYTHONPATH.

An additional directory will be inserted in the search path in front of PYTHONPATH as described above under Interface options. The search path can be manipulated from within a Python program as the variable sys.path.

This will add a path to your Python process / instance (i.e. the running executable). The path will not be modified for any other Python processes. Another running Python program will not have its path modified, and if you exit your program and run again the path will not include what you added before. What are you are doing is generally correct.

set.py:

import sys
sys.path.append("/tmp/TEST")

loop.py

import sys
import time
while True:
  print sys.path
  time.sleep(1)

run: python loop.py &

This will run loop.py, connected to your STDOUT, and it will continue to run in the background. You can then run python set.py. Each has a different set of environment variables. Observe that the output from loop.py does not change because set.py does not change loop.py's environment.

A note on importing

Python imports are dynamic, like the rest of the language. There is no static linking going on. The import is an executable line, just like sys.path.append....