Arguably the easiest way to find the signature for a function would be help(function):

>>> def function(arg1, arg2="foo", *args, **kwargs): pass
>>> help(function)
Help on function function in module __main__:

function(arg1, arg2='foo', *args, **kwargs)

Also, in Python 3 a method was added to the inspect module called signature, which is designed to represent the signature of a callable object and its return annotation:

>>> from inspect import signature
>>> def foo(a, *, b:int, **kwargs):
...     pass

>>> sig = signature(foo)

>>> str(sig)
'(a, *, b:int, **kwargs)'

>>> str(sig.parameters['b'])
'b:int'

>>> sig.parameters['b'].annotation
<class 'int'>