You create a slice by calling slice with the same fields you would use if doing [start:end:step] notation:

Use with AIsl = slice(0,4)

To use the slice, just pass it as if it were the index into a list or string:

Use with AI>>> s = "ABCDEFGHIJKL"
>>> sl = slice(0,4)
>>> print(s[sl])
'ABCD'

Let's say you have a file of fixed-length text fields. You could define a list of slices to easily extract the values from each "record" in this file.

Use with AIdata = """\
0010GEORGE JETSON    12345 SPACESHIP ST   HOUSTON       TX
0020WILE E COYOTE    312 ACME BLVD        TUCSON        AZ
0030FRED FLINTSTONE  246 GRANITE LANE     BEDROCK       CA
0040JONNY QUEST      31416 SCIENCE AVE    PALO ALTO     CA""".splitlines()


fieldslices = [slice(*fielddef) for fielddef in [
    (0,4), (4, 21), (21,42), (42,56), (56,58),
    ]]
fields = "id name address city state".split()

for rec in data:
    for field,sl in zip(fields, fieldslices):
        print("{} : {}".format(field, rec[sl]))
    print('')

# or this same code using itemgetter, to make a function that
# extracts all slices from a string into a tuple of values
import operator
rec_reader = operator.itemgetter(*fieldslices)
for rec in data:
    for field, field_value in zip(fields, rec_reader(rec)):
        print("{} : {}".format(field, field_value))
    print('')

Prints:

Use with AIid : 0010
name : GEORGE JETSON    
address : 12345 SPACESHIP ST   
city : HOUSTON       
state : TX

id : 0020
name : WILE E COYOTE    
address : 312 ACME BLVD        
city : TUCSON        
state : AZ

id : 0030
name : FRED FLINTSTONE  
address : 246 GRANITE LANE     
city : BEDROCK       
state : CA

id : 0040
name : JONNY QUEST      
address : 31416 SCIENCE AVE    
city : PALO ALTO     
state : CA

The syntax is:

Use with AIa[start:stop]  # items start through stop-1
a[start:]      # items start through the rest of the array
a[:stop]       # items from the beginning through stop-1
a[:]           # a copy of the whole array

There is also the step value, which can be used with any of the above:

Use with AIa[start:stop:step] # start through not past stop, by step

The key point to remember is that the :stop value represents the first value that is not in the selected slice. So, the difference between stop and start is the number of elements selected (if step is 1, the default).

The other feature is that start or stop may be a negative number, which means it counts from the end of the array instead of the beginning. So:

Use with AIa[-1]    # last item in the array
a[-2:]   # last two items in the array
a[:-2]   # everything except the last two items

Similarly, step may be a negative number:

Use with AIa[::-1]    # all items in the array, reversed
a[1::-1]   # the first two items, reversed
a[:-3:-1]  # the last two items, reversed
a[-3::-1]  # everything except the last two items, reversed

Python is kind to the programmer if there are fewer items than you ask for. For example, if you ask for a[:-2] and a only contains one element, you get an empty list instead of an error. Sometimes you would prefer the error, so you have to be aware that this may happen.

Relationship with the slice object

A slice object can represent a slicing operation, i.e.:

Use with AIa[start:stop:step]

is equivalent to:

Use with AIa[slice(start, stop, step)]

Slice objects also behave slightly differently depending on the number of arguments, similar to range(), i.e. both slice(stop) and slice(start, stop[, step]) are supported. To skip specifying a given argument, one might use None, so that e.g. a[start:] is equivalent to a[slice(start, None)] or a[::-1] is equivalent to a[slice(None, None, -1)].

While the :-based notation is very helpful for simple slicing, the explicit use of slice() objects simplifies the programmatic generation of slicing.

Use None everywhere the syntax-based slice uses a blank value:

someseq[slice(2, None)]

is equivalent to:

someseq[2:]

Similarly, someseq[:10:2] can use a preconstructed slice defined with slice(None, 10, 2), etc.