You can use ndiff in the difflib module to do this. It has all the information necessary to convert one string into another string.

A simple example:

import difflib

cases=[('afrykanerskojęzyczny', 'afrykanerskojęzycznym'),
       ('afrykanerskojęzyczni', 'nieafrykanerskojęzyczni'),
       ('afrykanerskojęzycznym', 'afrykanerskojęzyczny'),
       ('nieafrykanerskojęzyczni', 'afrykanerskojęzyczni'),
       ('nieafrynerskojęzyczni', 'afrykanerskojzyczni'),
       ('abcdefg','xac')] 

for a,b in cases:     
    print('{} => {}'.format(a,b))  
    for i,s in enumerate(difflib.ndiff(a, b)):
        if s[0]==' ': continue
        elif s[0]=='-':
            print(u'Delete "{}" from position {}'.format(s[-1],i))
        elif s[0]=='+':
            print(u'Add "{}" to position {}'.format(s[-1],i))    
    print()      

prints:

afrykanerskojęzyczny => afrykanerskojęzycznym
Add "m" to position 20

afrykanerskojęzyczni => nieafrykanerskojęzyczni
Add "n" to position 0
Add "i" to position 1
Add "e" to position 2

afrykanerskojęzycznym => afrykanerskojęzyczny
Delete "m" from position 20

nieafrykanerskojęzyczni => afrykanerskojęzyczni
Delete "n" from position 0
Delete "i" from position 1
Delete "e" from position 2

nieafrynerskojęzyczni => afrykanerskojzyczni
Delete "n" from position 0
Delete "i" from position 1
Delete "e" from position 2
Add "k" to position 7
Add "a" to position 8
Delete "ę" from position 16

abcdefg => xac
Add "x" to position 0
Delete "b" from position 2
Delete "d" from position 4
Delete "e" from position 5
Delete "f" from position 6
Delete "g" from position 7

If you don't have to use difflib, you could use a set and string splitting!

>>> original = "Apple Microsoft Google Oracle"
>>> edited = "Apple Nvdia IBM"
>>> set(original.split()).symmetric_difference(set(edited.split()))
{'IBM', 'Google', 'Oracle', 'Microsoft', 'Nvdia'}

You can also get the shared members with the .intersection()

>>> set(original.split()).intersection(set(edited.split()))
{'Apple'}

The Wikipedia has a good section on basic set operations with accompanying Venn diagrams
https://en.wikipedia.org/wiki/Set_(mathematics)#Basic_operations

However, if you have to use difflib (some strange environment or assignment) you can also just find every member with a +- prefix and slice off the all the prefixes

>>> diff = d.compare(original.split(), edited.split())
>>> list(a[2:] for a in diff if a.startswith(("+", "-")))
['Nvdia', 'IBM', 'Microsoft', 'Google', 'Oracle']

All of these operations result in an iterable of strings, so you can .join() 'em together or similar to get a single result as you do in your Question

>>> print("\n".join(result))
IBM
Google
Oracle
Microsoft
Nvdia

import difflib

>>> a = 'alex is a buff dude'
>>> b = 'a;exx is a buff dud'
>>> difflib.SequenceMatcher(None, a, b).ratio()

0.89473684210526316