some_list[-1] is the shortest and most Pythonic.
In fact, you can do much more with this syntax. The some_list[-n] syntax gets the nth-to-last element. So some_list[-1] gets the last element, some_list[-2] gets the second to last, etc, all the way down to some_list[-len(some_list)], which gives you the first element.
You can also set list elements in this way. For instance:
>>> some_list = [1, 2, 3]
>>> some_list[-1] = 5 # Set the last element
>>> some_list[-2] = 3 # Set the second to last element
>>> some_list
[1, 3, 5]
Note that getting a list item by index will raise an IndexError if the expected item doesn't exist. This means that some_list[-1] will raise an exception if some_list is empty, because an empty list can't have a last element.
some_list[-1] is the shortest and most Pythonic.
In fact, you can do much more with this syntax. The some_list[-n] syntax gets the nth-to-last element. So some_list[-1] gets the last element, some_list[-2] gets the second to last, etc, all the way down to some_list[-len(some_list)], which gives you the first element.
You can also set list elements in this way. For instance:
>>> some_list = [1, 2, 3]
>>> some_list[-1] = 5 # Set the last element
>>> some_list[-2] = 3 # Set the second to last element
>>> some_list
[1, 3, 5]
Note that getting a list item by index will raise an IndexError if the expected item doesn't exist. This means that some_list[-1] will raise an exception if some_list is empty, because an empty list can't have a last element.
If your str() or list() objects might end up being empty as so: astr = '' or alist = [], then you might want to use alist[-1:] instead of alist[-1] for object "sameness".
The significance of this is:
alist = []
alist[-1] # will generate an IndexError exception whereas
alist[-1:] # will return an empty list
astr = ''
astr[-1] # will generate an IndexError exception whereas
astr[-1:] # will return an empty str
Where the distinction being made is that returning an empty list object or empty str object is more "last element"-like then an exception object.
Here's a way, although it looks odd:
(list or [None])[-1]
I find this more readable than @Alex's answer
lst = [1, 3, 2]
print None if not lst else lst[-1]
Edit: Though must admit, it is the first time I encountered that usage. Always thought those expressions returned bool type :)