Hedge suggests a 20-8-2 pattern based on his research and real-world testing: Sit for 20 minutes, stand for 8, stretch or walk around for 2, and repeat. These numbers aren't absolute, but what's most important is not to stay in one position for too long, Hedge said. We also recommend looking at our guide to the best standing desk mat if you find you regularly fatigue while standing.

During the workday, you should be doing a mixture of standing, sitting, and moving, if possible, said Alan Hedge, a certified ergonomist and professor emeritus in the Department of Design and Environmental Analysis at Cornell University. "Mixing things up reduces any negative effects [of sitting or standing] in terms of musculoskeletal discomfort, your level of alertness, or productivity," Hedge said. Standing desks make it much easier to transition from sitting to standing while keeping proper posture and ergonomics in mind.