Yes. Bose QuietComfort 45 headphones have an adaptive microphone system that allows you to use the headphones during calls when connected to any smartphone. In addition to traditional calls, the headphones will work with many apps that use Voice over Internet Protocol (VoIP), such as Zoom or FaceTime. The microphone system adapts to your environment to isolate your voice from competing background noises and wind so that you can confidently take a call or speak to your voice assistant anywhere you go — knowing you will be heard clearly and naturall

While both provide world-class noise cancelling, high-quality audio performance and a comfortable fit, there are a few key differences. QuietComfort 45 headphones have 2 modes of noise cancellation — Quiet Mode and Aware Mode. Bose Headphones 700 offer more customization, with 11 levels of noise cancelling. Bose Headphones 700 also offer the convenience of capacitive touch controls and hands-free access to Amazon Alexa, Google Assistant, and your phone’s native voice assistant, like Siri. For battery life, you’ll enjoy 24 hours with QuietComfort 45 headphones and up to 20 hours with Bose Headp

To change the noise cancelling mode, you can press the Action button. A voice prompt will announce the selected mode. You can also change the noise cancelling mode using the Bose Music app. For more information, see page 21 of the manual.