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How is the word 'unique' distinct from other similar adjectives?
Some common synonyms of unique are eccentric, erratic, odd, outlandish, peculiar, quaint, singular, and strange. While all these words mean "departing from what is ordinary, usual, or to be expected," unique implies singularity and the fact of being without a known parallel.
// a career unique in the annals of science
Where would 'odd' be a reasonable alternative to 'unique'?
The words odd and unique are synonyms, but do differ in nuance. Specifically, odd applies to a departure from the regular or expected.
// an odd sense of humor
When might 'quaint' be a better fit than 'unique'?
Although the words quaint and unique have much in common, quaint suggests an old-fashioned but pleasant oddness.
// a quaint fishing village
Maybe novel captures some of the meaning you're trying to convey? It suggests something out of the ordinary and interesting.
Verification of space weather forecasts presents novel challenges when compared with other types of forecasts.
"Extraordinary", "uncommon", "incomparable". "Rare" might also work here.