function _arrayBufferToBase64( buffer ) {
    var binary = '';
    var bytes = new Uint8Array( buffer );
    var len = bytes.byteLength;
    for (var i = 0; i < len; i++) {
        binary += String.fromCharCode( bytes[ i ] );
    }
    return window.btoa( binary );
}

but, non-native implementations are faster e.g. https://gist.github.com/958841 see http://jsperf.com/encoding-xhr-image-data/6

jsPerf.com is jsPerf.app now: https://jsperf.app/encoding-xhr-image-data/51

Updated benchmarks: https://jsben.ch/wnaZC

function base64ToArrayBuffer(base64) {
    var binaryString = atob(base64);
    var bytes = new Uint8Array(binaryString.length);
    for (var i = 0; i < binaryString.length; i++) {
        bytes[i] = binaryString.charCodeAt(i);
    }
    return bytes.buffer;
}

function base64ToArrayBuffer(base64) {
    var binaryString = atob(base64);
    var bytes = new Uint8Array(binaryString.length);
    for (var i = 0; i < binaryString.length; i++) {
        bytes[i] = binaryString.charCodeAt(i);
    }
    return bytes.buffer;
}

function base64ToArrayBuffer(base64) {
    var binaryString = atob(base64);
    var bytes = new Uint8Array(binaryString.length);
    for (var i = 0; i < binaryString.length; i++) {
        bytes[i] = binaryString.charCodeAt(i);
    }
    return bytes.buffer;
}