4-1/4" and some larger wall tiles have bumps cast in that act as spacers. Unless you want a larger gap, no additional spacers are needed.
Whether your particular tile has them is uncertain. They're often necessary to prevent sagging with heavier tile while the mortar or mastic sets.
Answer from isherwood on Stack ExchangeVideos
I’m seeing conflicting guidance on what spacing to use with these tiles; and if spacers are required.
The sides have a slight bevel such that the tops are just under 1/16” apart. In my testing with 1/16” spacers, the grout line ends up at 1/8” which is visually much thicker than I prefer. I’m trying to minimize the grout lines as much as possible.
What would you do in this case?
**Tiles are 2x8 inches. This will be a kitchen backsplash
I recently purchased some Daltile subway tiles from home Depot. I'm realizing now that they have "built in lugs" to space them 1/16" apart without having to use separate spacers. Has any one used tiles like this? I want the 1/16 grout lines, but am worried that the grout may fall out as it can't penatrate as deep between the tiles as standard spacers. I plan on using Custom Fusion Pro grout as this is for a shower.
Thanks in advance!