If you consider that hexadecimal is base 16, its actually quite easy:

Start from the least significant digit and work towards the most significant (right to left) and multiply the digit with increasing powers of 16, then sum the result.

For example:

0x12 = 2 + (1 * 16) = 18

0x99 = 9 + (9 * 16) = 153

Then, remember that A = 10, B = 11, C = 12, D = 13, E = 14 and F = 15

So,

0xFB = 11 + (15 * 16) = 251

Answer from Andre Miller on Stack Overflow
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