You can install spacy and download en in the jupyter notebook as:

import sys
!{sys.executable} -m pip install spacy
!{sys.executable} -m spacy download en

In order to load the model you need to download it first, if you are doing it on your local machine.(not on google colab). So after

pip install -U spacy

you need to download using

python -m spacy download de_core_news_sm

Then,

nlp = spacy.load('de_core_news_sm') 

Google Colaboratory

In case of trying it in google colab,

pip install -U spacy
import spacy.cli
spacy.cli.download("de_core_news_sm")

You can also add virtual environment then use spacy after activating in virtual environment.

python3 -m venv <name_of_virtualenv>
# to activate 
source /pathtovirenc/<name_of_virtualenv>/bin/activate

#then use the above commands
pip3 install -U spacy
python3 -m spacy download de_core_news_sm