Watch out if you are aiming at integers, like 1,2,3,4,5. If you intend to use the elements of your array as integers and not as strings after splitting the string, consider converting them into such.

var str = "1,2,3,4,5,6";
var temp = new Array();
// This will return an array with strings "1", "2", etc.
temp = str.split(",");

Adding a loop like this,

for (a in temp ) {
    temp[a] = parseInt(temp[a], 10); // Explicitly include base as per Álvaro's comment
}

will return an array containing integers, and not strings.

Use the split function which is available for strings and convert the numbers to actual numbers, not strings.

var ar = "'California',51.2154,-95.2135464,'data'".split(",");

for (var i = ar.length; i--;) {
  var tmp = parseFloat(ar[i]);
  ar[i] = (!isNaN(tmp)) ? tmp : ar[i].replace(/['"]/g, "");
}

console.log(ar)

Beware, this will fail if your string contains arrays/objects.

In JSON, numbers don't need double quotes, so you could just append [ and ] to either end of the string, resulting in the string "[1,4,5,11,58,96]" and you will have a JSON Array of numbers.

You can use split() to get string array from comma separated string. If you iterate and perform mathematical operation on element of string array then that element will be treated as number by run-time cast but still you have string array. To convert comma separated string int array see the edit.

arr = strVale.split(',');

Live Demo

var strVale = "130,235,342,124";
arr = strVale.split(',');
for(i=0; i < arr.length; i++)
    console.log(arr[i] + " * 2 = " + (arr[i])*2);

Output

130 * 2 = 260
235 * 2 = 470
342 * 2 = 684
124 * 2 = 248

Edit, Comma separated string to int Array In the above example the string are casted to numbers in expression but to get the int array from string array you need to convert it to number.

var strVale = "130,235,342,124";
var strArr = strVale.split(',');
var intArr = [];
for(i=0; i < strArr.length; i++)
   intArr.push(parseInt(strArr[i]));