I used the idea from Kerry's answer, but I simplified it since I was just looking for something simple for my specific purpose. Here is what I have:

function numberWithCommas(x) {
    return x.toString().replace(/\B(?=(\d{3})+(?!\d))/g, ",");
}

function numberWithCommas(x) {
    return x.toString().replace(/\B(?<!\.\d*)(?=(\d{3})+(?!\d))/g, ",");
}

function test(x, expect) {
    const result = numberWithCommas(x);
    const pass = result === expect;
    console.log(`${pass ? "✓" : "ERROR ====>"} {result}`);
    return pass;
}

let failures = 0;
failures += !test(0,        "0");
failures += !test(100,      "100");
failures += !test(1000,     "1,000");
failures += !test(10000,    "10,000");
failures += !test(100000,   "100,000");
failures += !test(1000000,  "1,000,000");
failures += !test(10000000, "10,000,000");
if (failures) {
    console.log(`${failures} test(s) failed`);
} else {
    console.log("All tests passed");
}

.as-console-wrapper {
    max-height: 100% !important;
}

The regex uses two lookahead assertions:

• a positive one to look for any point in the string that has a multiple of 3 digits in a row after it,
• a negative assertion to make sure that point only has exactly a multiple of 3 digits. The replacement expression puts a comma there.

For example, if you pass it 123456789.01, the positive assertion will match every spot to the left of the 7 (since 789 is a multiple of 3 digits, 678 is a multiple of 3 digits, 567, etc.).

The negative assertion checks that the multiple of 3 digits does not have any digits after it. 789 has a period after it so it is exactly a multiple of 3 digits, so a comma goes there. 678 is a multiple of 3 digits, but it has a 9 after it, so those 3 digits are part of a group of 4, and a comma does not go there. Similarly for 567.

456789 is 6 digits, which is a multiple of 3, so a comma goes before that. 345678 is a multiple of 3, but it has a 9 after it, so no comma goes there. And so on. The \B keeps the regex from putting a comma at the beginning of the string.

neu-rah mentioned that this function adds commas in undesirable places if there are more than 3 digits after the decimal point. If this is a problem, you can use this function:

function numberWithCommas(x) {
    var parts = x.toString().split(".");
    parts[0] = parts[0].replace(/\B(?=(\d{3})+(?!\d))/g, ",");
    return parts.join(".");
}

function numberWithCommas(x) {
    var parts = x.toString().split(".");
    parts[0] = parts[0].replace(/\B(?=(\d{3})+(?!\d))/g, ",");
    return parts.join(".");
}

function test(x, expect) {
    const result = numberWithCommas(x);
    const pass = result === expect;
    console.log(`${pass ? "✓" : "ERROR ====>"} {result}`);
    return pass;
}

let failures = 0;
failures += !test(0              , "0");
failures += !test(0.123456       , "0.123456");
failures += !test(100            , "100");
failures += !test(100.123456     , "100.123456");
failures += !test(1000           , "1,000");
failures += !test(1000.123456    , "1,000.123456");
failures += !test(10000          , "10,000");
failures += !test(10000.123456   , "10,000.123456");
failures += !test(100000         , "100,000");
failures += !test(100000.123456  , "100,000.123456");
failures += !test(1000000        , "1,000,000");
failures += !test(1000000.123456 , "1,000,000.123456");
failures += !test(10000000       , "10,000,000");
failures += !test(10000000.123456, "10,000,000.123456");
if (failures) {
    console.log(`${failures} test(s) failed`);
} else {
    console.log("All tests passed");
}

.as-console-wrapper {
    max-height: 100% !important;
}

T.J. Crowder pointed out that now that JavaScript has lookbehind (support info), it can be solved in the regular expression itself:

function numberWithCommas(x) {
    return x.toString().replace(/\B(?<!\.\d*)(?=(\d{3})+(?!\d))/g, ",");
}

function numberWithCommas(x) {
    return x.toString().replace(/\B(?<!\.\d*)(?=(\d{3})+(?!\d))/g, ",");
}

function test(x, expect) {
    const result = numberWithCommas(x);
    const pass = result === expect;
    console.log(`${pass ? "✓" : "ERROR ====>"} {result}`);
    return pass;
}

let failures = 0;
failures += !test(0,               "0");
failures += !test(0.123456,        "0.123456");
failures += !test(100,             "100");
failures += !test(100.123456,      "100.123456");
failures += !test(1000,            "1,000");
failures += !test(1000.123456,     "1,000.123456");
failures += !test(10000,           "10,000");
failures += !test(10000.123456,    "10,000.123456");
failures += !test(100000,          "100,000");
failures += !test(100000.123456,   "100,000.123456");
failures += !test(1000000,         "1,000,000");
failures += !test(1000000.123456,  "1,000,000.123456");
failures += !test(10000000,        "10,000,000");
failures += !test(10000000.123456, "10,000,000.123456");
if (failures) {
    console.log(`${failures} test(s) failed`);
} else {
    console.log("All tests passed");
}

.as-console-wrapper {
    max-height: 100% !important;
}

(?<!\.\d*) is a negative lookbehind that says the match can't be preceded by a . followed by zero or more digits. The negative lookbehind is faster than the split and join solution (comparison), at least in V8.

This seems to work

var formatNumber = function(num) {
    return parseFloat(num).toFixed(2).toLocaleString();
};

Edit: Sept 18, 2019

Since new APIs are available, thought it would be helpful to point out that you can do this much more simply using toLocaleString options:

const numbers = [1, 1000, 2345.67, 21589.334719999995];
const options = { 
  minimumFractionDigits: 2,
  maximumFractionDigits: 2 
};
numbers.forEach(num => {
  const formatted = Number(num).toLocaleString('en', options);
  console.log(formatted);
});

original answer

To add the commas, you could use:

n = parseFloat(n).toFixed(2)
var withCommas = Number(n).toLocaleString('en');

Here is a fiddle