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UpToDate
uptodate.com › contents › central-hypothyroidism › print
Central hypothyroidism
UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide.
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Ucsf
ccpd.ucsf.edu › pituitary-disorders › hormonal-conditions › hypothyroidism
Hypothyroidism | California Center for Pituitary Disorders
Typically, loss of TSH secretion ... of an expanding pituitary tumor. Treatment of most types of hypothyroidism is successful with replacement therapy with thyroxine, which is adjusted until normal serum hormone levels are achieved....
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Healthline
healthline.com › health › hypothryroidism › pituitary-hypothyroidism
Pituitary Hypothyroidism: Causes, Symptoms, and Treatment
March 23, 2023 - Treating pituitary hypothyroidism ... hormone thyroxin. The · first-line treatment is usually levothyroxine for primary, secondary, and tertiary hypothyroidism....
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Verywell Health
verywellhealth.com › pituitary-hypothyroidism-5272133
Pituitary Hypothyroidism: Causes, Symptoms, Treatment
September 15, 2025 - Pituitary hypothyroidism, or secondary hypothyroidism, is caused by failure of the pituitary gland. Learn how to identify and treat this condition.
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UCLA Health
uclahealth.org › medical-services › surgery › endocrine-surgery › patient-resources › patient-education › endocrine-surgery-encyclopedia › hypothyroidism-secondary
Hypothyroidism Secondary - Endocrine Surgery | UCLA Health
In patients who have hypothyroidism caused by a pituitary tumor, surgery may be required. However, surgery may not cure the hypothyroidism, and thyroid replacement will still be needed.
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NCBI
ncbi.nlm.nih.gov › books › NBK562316
Pituitary Hyperplasia in Primary Hypothyroidism - StatPearls - NCBI Bookshelf
August 28, 2023 - Pituitary hyperplasia is an under-recognized manifestation that can occur fairly commonly in primary hypothyroidism. Recognition of this entity is important as the primary modality of treatment is mainly thyroid hormone replacement and not surgery.
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Mayo Clinic
mayoclinic.org › diseases-conditions › hypopituitarism › diagnosis-treatment › drc-20351648
Hypopituitarism - Diagnosis and treatment - Mayo Clinic
February 13, 2024 - Learn about the symptoms and treatment of this rare condition caused by a problem with the pituitary gland.
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Cleveland Clinic
my.clevelandclinic.org › health › diseases › 12120-hypothyroidism
Hypothyroidism (Underactive Thyroid): Symptoms & Treatment
September 11, 2025 - Hashimoto’s disease is the most common cause of hypothyroidism. It’s an autoimmune disease, so it happens when your immune system attacks your thyroid. ... Certain medications, including lithium, thalidomide and amiodarone. Conditions present at birth, like being born with no thyroid gland or a thyroid gland that doesn’t work properly. Iodine deficiency (when you don’t have enough iodine in your body). Pituitary gland disorders, including noncancerous tumors.
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American Thyroid Association
thyroid.org › home › patients portal › clinical thyroidology for the public › vol 4 issue 6 › vol 4 issue 6 p.14-15
Vol 4 Issue 6 p.14-15 | American Thyroid Association
July 10, 2017 - The pituitary gland secretes TSH to control thyroid function. Hypothyroidism: a condition where the thyroid gland is underactive and doesn’t produce enough thyroid hormone. Treatment requires taking thyroid hormone pills.
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Getlabtest
getlabtest.com › news › post › pituitary-hypothyroidism-causes-treatment
Pituitary Hypothyroidism: Causes and Treatment Insights
Treatment primarily involves thyroid hormone replacement therapy with levothyroxine. Dosing is carefully managed through regular blood tests and symptom monitoring, with adjustments made as needed.
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NCBI
ncbi.nlm.nih.gov › books › NBK519536
Hypothyroidism - StatPearls - NCBI Bookshelf
February 18, 2024 - The less commonly seen secondary ... hypothyroidism is rare. The drug of choice for the treatment of hypothyroidism of any etiology is thyroid hormone replacement....
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Verywell Health
verywellhealth.com › secondary-hypothyroidism-5272471
Secondary Hypothyroidism: Causes, Symptoms, Treatment
October 16, 2025 - Secondary hypothyroidism happens ... Symptoms include fatigue, dry skin, joint and muscle pain, and weight gain. Thyroid hormone replacement therapy is the standard treatment to restore normal thyroid levels....
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Endocrinologyadvisor
endocrinologyadvisor.com › home › ddi › central hypothyroidism
Central Hypothyroidism - Endocrinology Advisor
August 13, 2025 - Central hypothyroidism treatment includes thyroid hormone replacement with levothyroxine. Pituitary hormone deficiencies should be treated with glucocorticoids.
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BMJ Best Practice
bestpractice.bmj.com › topics › en-us › 36
Central hypothyroidism - Symptoms, diagnosis and treatment | BMJ Best Practice US
In central hypothyroidism, free T4 is low and TSH may be low, normal, or minimally elevated. Magnetic resonance imaging may reveal a sellar or parasellar mass or infiltrative disorder. Treatment of central hypothyroidism is by thyroid hormone replacement (levothyroxine).
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ScienceDirect
sciencedirect.com › science › article › pii › S0303720721000174
The hypothalamus-pituitary-thyroid (HPT)-axis and its role in physiology and pathophysiology of other hypothalamus-pituitary functions - ScienceDirect
February 4, 2021 - As an aid in this direction the present review summarizes and highlights the importance of the hypothalamus-pituitary-thyroid axis, pitfalls in diagnosing central hypothyroidism, diagnosing/testing central hypothyroidism in relation to panhypopituitarism, pointing at interactions of the thyroid function with other pituitary hormones, as well as local hypothalamic neurotransmitters and gut-brain hormones. Furthermore, the treatment effect of each axis on the regulation of the others is described.
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Johns Hopkins Medicine
hopkinsmedicine.org › health › conditions-and-diseases › hypothyroidism
Hypothyroidism | Johns Hopkins Medicine
Another cause may be treatment for an overactive thyroid gland. That may include radioactive iodine therapy or surgery. Hypothyroidism may also develop shortly after pregnancy. A condition called secondary hypothyroidism can also sometimes happen. It’s when your pituitary gland does not make ...
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Ucsf
ccpd.ucsf.edu › news › ask-expert-central-hypothyroidism
Ask the Expert: Central Hypothyroidism | California Center for Pituitary Disorders
As a result, TSH levels are not as useful in evaluating for possible pituitary deficiency nor are they useful in the evaluation of the adequacy of the dose of thyroid hormone replacement in hypopituitary patients. Successful treatment involves the administration of thyroxine in the form of l-T4 in ...
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Healthline
healthline.com › health › hypothryroidism › central-hypothyroidism
Central Hypothyroidism: Symptoms, Treatment, and More
December 21, 2023 - Central hypothyroidism is a rare form of hypothyroidism. It occurs when the pituitary gland or hypothalamus (or both) doesn’t produce the hormones your thyroid gland needs to function properly. This may be due to a tumor, a brain injury, or a genetic issue. When you receive the right treatment, the symptoms of central hypothyroidism may become more manageable or disappear altogether.
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Barrow Neurological Institute
barrowneuro.org › condition › thyroid-stimulating-hormone-tumor
Thyroid-Stimulating Hormone (TSH) Tumor | Barrow Neurological Institute
1 week ago - ... Most symptoms of a TSH-producing ... have a TSH adenoma, you may experience the following: ... Surgery is the best form of treatment and the only way to achieve a cure....
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American Academy of Family Physicians
aafp.org › pubs › afp › issues › 2021 › 0515 › p605.html
Hypothyroidism: Diagnosis and Treatment | AAFP
May 15, 2021 - Most patients with subclinical ... from treatment unless the thyroid-stimulating hormone level is greater than 10 mIU per L or the thyroid peroxidase antibody is elevated. Hypothyroidism occurs when there is inadequate thyroid hormone production by the thyroid gland or insufficient stimulation by the hypothalamus or pituitary ...