you need have a windows desktop session on aws vm, you need keep the desptop on aws, don't lock screen automatically, you can find one always on machine, rdp to the aws vm. keep rdp connneciton on.

for more about windows session, station, desktop, you can refer to: https://techcommunity.microsoft.com/t5/ask-the-performance-team/sessions-desktops-and-windows-stations/ba-p/372473#:~:text=A%20desktop%20is%20a%20session-specific%20paged%20pool%20area,and%20each%20windows%20station%20can%20have%20multiple%20desktops.

Answer from justin on Stack Overflow
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Slashdot
slashdot.org › software › p › PyAutoGUI › alternatives
Top PyAutoGUI Alternatives in 2026
As an enhancement to the Windows console window, this local terminal emulator allows users to manage multiple consoles and simple GUI applications, such as PuTTY, within a single customizable tabbed interface equipped with a variety of features. It initiates console programs within a concealed console window, offering an alternative customizable graphical interface that boasts numerous capabilities.
Discussions

python - Alternative to pyautogui for desktop automation - Stack Overflow
I have created a software that processes images to do automation of desktop application Itunes. It is working fine but I want it to run on servers. But it would not have visual data while on server... More on stackoverflow.com
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python - better way to automate mouse&keyboard using pyautogui - Stack Overflow
is there another way of interacting ... exclude alternatives? 2017-02-23T10:10:53.627Z+00:00 ... Find the answer to your question by asking. Ask question ... See similar questions with these tags. ... New site design and philosophy for Stack Overflow: Starting February 24, 2026... ... 7 How to automate without forfeiting keyboard/mouse control (similar to selenium's controlled window) 0 Controlling the mouse and browser with pyautogui for process ... More on stackoverflow.com
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PyAutoGUI vs Pywinauto
PyAutoGUI gives you the option to send keyboard and mouse clicks and do screenshots, not much more. Pywinauto tries to let you interact with the element of a windows application, so also works, if the program is not in the foreground. I've played with Pywinauto and am not entirely happy. If you want to automate a complicated GUI program, one that contantly opens and closes windows and message boxes, their approach of locating the part of the program that you want to react to can drive you mad. I had to write a lot of try/catch code to get it to work at all. PyWinGUI alas isn't better for this usecase, but at least very easy to use. On windows 10 you also have the option of getting autohotkey (not python, but its own language) which does a much better job at automating, but has horrible syntax and no data structures... More on reddit.com
🌐 r/Python
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April 13, 2018
Best tool to automate GUI (like AutoHotKey, PyAutoGUI)?
If this is for personal use and doesn’t need to be shared with others then pyautogui can handle the image detection, mouse clicks, and text entry. I don’t believe it meets all of your requirements but it is very simple to pick up and I’ve had non-Python programmers (SAS) following the syntax within minutes. More on reddit.com
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March 21, 2021
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SourceForge
sourceforge.net › software › product › PyAutoGUI › alternatives
Best PyAutoGUI Alternatives & Competitors
ConEmu starts a console program in a hidden console window, and provides an alternative customizable GUI window with various features. Smooth and friendly window resizing; tabs for editors, viewers, panels and consoles. Run simple GUI apps like PuTTY in tabs. Windows 7 Jump Lists and Progress on Taskbar buttons. Easily run old DOS applications (games) in Windows 7 or 64-bit OS. Thumbnails and tiles in Far Manager. Normal, maximized and full screen graphical window modes. Compare vs. PyAutoGUI View Software
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Software Suggest
softwaresuggest.com › home › task automation software › pyautogui › pyautogui alternatives
11 Best PyAutoGUI Alternatives & Competitors in 2026
March 1, 2026 - Top paid & free alternatives to PyAutoGUI includes RoboTask, Magical, AutoHotkey, Macro Express, JitBit Macro Recorder, Axiom.ai, Automa, pywinauto, FastKeys and GoLess. Analyze a range of top Task Automation Software that offer similar benefits ...
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StackShare
stackshare.io › pypi-pyautogui › alternatives
PyAutoGUI Alternatives
2,513 stacks0 votes24 followersCompare PyAutoGUI vs pytest →
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TestDriver
testdriver.ai › articles › top-4-open-source-alternatives-to-pyautogui
Top 4 Open Source Alternatives to PyAutoGUI
September 24, 2025 - TestDriver - AI-powered end-to-end testing. Automate your tests with natural language using computer vision.
Find elsewhere
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BlackHatWorld
blackhatworld.com › home › forums › programming & web design › programming
Tools Similar to PyAutoGUI for Automating Desktop Applications | BlackHatWorld
November 21, 2024 - PyAutoGUI is a great tool, but it has limitations, particularly in terms of inspecting elements. It primarily works by image recognition or positional tracking, both of which can be unreliable due to changes in position or similarities in images. A more robust solution would ideally allow for element inspection, making it more adaptable to dynamic interfaces. Click to expand... I think the most popular alternative would be AutoHotkey, but if you want to use python then you should use PyWinAuto
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StackShare
stackshare.io › stackups › pypi-pyautogui-vs-pypi-selenium
selenium vs PyAutoGUI | What are the differences? | StackShare
Task Automation: Selenium is widely used for web testing purposes, allowing users to automate browser tasks, perform functional testing, and run test scripts. PyAutoGUI, on the other hand, is more suitable for general-purpose task automation, allowing users to automate repetitive tasks outside the web browser, such as GUI-based software testing, data entry, or image recognition.
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Reddit
reddit.com › r/python › pyautogui vs pywinauto
r/Python on Reddit: PyAutoGUI vs Pywinauto
April 13, 2018 -

What is the difference between the two and which one is better?

(I'm using windows 10. )

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Testdriver
testdriver.ai › articles › top-12-alternatives-to-pyautogui-for-windows-macos-linux-testing
Top 12 Alternatives to PyAutoGUI for Windows/macOS/Linux Testing - TestDriver
September 24, 2025 - RobotJS is preferable for JS/TS teams; PyAutoGUI fits Python teams. Both lack deep object awareness; consider object-aware alternatives for complex UIs.
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GitHub
github.com › OguzhanUmutlu › jsautogui
GitHub - OguzhanUmutlu/jsautogui: JSAutoGUI is an npm package for node.js. Inspired by pyautogui from python. (but noticably faster and better)
JSAutoGUI is an npm package for node.js. Inspired by pyautogui from python. (but noticably faster and better) - OguzhanUmutlu/jsautogui
Starred by 48 users
Forked by 3 users
Languages   C++ 66.7% | TypeScript 16.5% | JavaScript 11.8% | C 1.9% | Python 1.8% | CMake 1.3% | C++ 66.7% | TypeScript 16.5% | JavaScript 11.8% | C 1.9% | Python 1.8% | CMake 1.3%
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Libhunt
python.libhunt.com › pyautogui-alternatives
PyAutoGUI Alternatives - Python GUI / Web Testing | LibHunt
August 20, 2024 - A cross-platform GUI automation Python module for human beings. Used to programmatically control the mouse & keyboard. Tags: Testing, GUI / Web Testing.
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eBool
ebool.com › alternatives › pyautogui-2
Top 15 PyAutoGUI Alternatives & Similar Software - eBool
The Top Alternatives to PyAutoGUI Includes IBM Watson Orchestrate, pywinauto, Warpdrive, AutoHotkey and 11 other products in Task Automation Software
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PyPI
pypi.org › project › PyDirectInput
PyDirectInput · PyPI
February 18, 2020 - This package is intended to be used in conjunction with PyAutoGUI. You can continue to use PyAutoGUI for all of its cool features and simply substitute in PyDirectInput for the inputs that aren't working.
      » pip install PyDirectInput
    
Published   Feb 02, 2021
Version   1.0.4
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Automate the Boring Stuff
automatetheboringstuff.com › 2e › chapter20
20 controlling the keyboard and mouse with gui automation
Some companies sell innovative (and pricey) “automation solutions,” usually marketed as robotic process automation (RPA). These products are effectively no different than the Python scripts you can make yourself with the pyautogui module, which has functions for simulating mouse movements, ...
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LibHunt
libhunt.com › r › pyautogui
PyAutoGUI Alternatives and Reviews (Feb 2024)
Which is the best alternative to PyAutoGUI? Based on common mentions it is: CPython, Runelite, Komorebi, Skhd, Fsearch, PySimpleGUI, Sxhkd, Letta, AHK_X11 or Sun-Valley-ttk-theme