Just convert it to timestamp

datetime.datetime.fromtimestamp(ms/1000.0)

In Python 3 this can be done in 2 steps:

1. Convert timestring to datetime object
2. Multiply the timestamp of the datetime object by 1000 to convert it to milliseconds.

For example like this:

from datetime import datetime

dt_obj = datetime.strptime('20.12.2016 09:38:42,76',
                           '%d.%m.%Y %H:%M:%S,%f')
millisec = dt_obj.timestamp() * 1000

print(millisec)

Output:

1482223122760.0

strptime accepts your timestring and a format string as input. The timestring (first argument) specifies what you actually want to convert to a datetime object. The format string (second argument) specifies the actual format of the string that you have passed.

Here is the explanation of the format specifiers from the official documentation:

• %d - Day of the month as a zero-padded decimal number.
• %m - Month as a zero-padded decimal number.
• %Y - Year with century as a decimal number
• %H - Hour (24-hour clock) as a zero-padded decimal number.
• %M - Minute as a zero-padded decimal number.
• %S - Second as a zero-padded decimal number.
• %f - Microsecond as a decimal number, zero-padded to 6 digits.

To get a date string with milliseconds, use [:-3] to trim the last three digits of %f (microseconds):

>>> from datetime import datetime
>>> datetime.utcnow().strftime('%Y-%m-%d %H:%M:%S.%f')[:-3]
'2022-09-24 10:18:32.926'

Or shorter:

>>> from datetime import datetime
>>> datetime.utcnow().strftime('%F %T.%f')[:-3]
'2022-09-24 10:18:32.926'

See the Python docs for more "%" format codes and the strftime(3) man page for the full list.