Tkinter: Easy, quick, in standard library. Not too many options, looks awful, cracks at the seam on complex things, documentation is between bad and non-existent. Custom-tkinter (look for it on github) makes it look better. Pyside6/PyQt6: Extremely powerful, has everything and 3 kitchen sinks, looks as good as you want, reliable. Pretty big learning curve, documentation is geared to c++, once you get in the qt boat you stay on the qt boat. html/CSS/Javascript. As complex as you want, good learning opportunity, can look amazing, usable on phone and tablet, final app is easy to distribute and update. Requires a server (that's huge!), need to learn multiple languages and frameworks so big learning curve, cannot center a div :) ! Answer from jimtk on reddit.com
Python
wiki.python.org › moin › GuiProgramming
GUI Programming in Python
Python has a huge number of GUI frameworks (or toolkits) available for it, from TkInter (traditionally bundled with Python, using Tk) to a number of other cross-platform solutions, as well as bindings to platform-specific (also known as "native") technologies.
Python GUIs
pythonguis.com
Python GUIs — Create GUI applications with Python and Qt
If you're new to creating GUIs with Python I now recommend starting with PyQt6. But we support other libraries too! Not sure which GUI library to use for your project?
What python GUIs do you recommend?
Tkinter: Easy, quick, in standard library. Not too many options, looks awful, cracks at the seam on complex things, documentation is between bad and non-existent. Custom-tkinter (look for it on github) makes it look better. Pyside6/PyQt6: Extremely powerful, has everything and 3 kitchen sinks, looks as good as you want, reliable. Pretty big learning curve, documentation is geared to c++, once you get in the qt boat you stay on the qt boat. html/CSS/Javascript. As complex as you want, good learning opportunity, can look amazing, usable on phone and tablet, final app is easy to distribute and update. Requires a server (that's huge!), need to learn multiple languages and frameworks so big learning curve, cannot center a div :) ! More on reddit.com
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February 23, 2024What is the state of Python GUI Libraries in 2025? Which one do you like and Why?
PySide(6) is definitely the most powerful option available. You don't have to worry about licensing unless you make changes to the original codebase. I would suggest avoiding any sort of GUI designer. Writing modular GUI components with code and then assembling them is far more robust. Qt Designer is clunky and leads to obfuscated code. Your DBBrowser screenshot could easily/quickly be created in PySide once you get the hang of the syntax. More on reddit.com
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April 15, 2025Is building a GUI always going to be THIS painful?
Do you have a minute to talk about our lord and savior flask? More on reddit.com
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February 23, 2025Best Python GUI libraries?
- Tkinter: It's built right into Python, making it super easy to get started. For a more modern look, check out CustomTkinter, which gives Tkinter a fresh coat of paint. - PyQt (or PySide6): These are powerful choices for creating professional, feature-rich desktop apps. They're based on the Qt library, so they're robust and work across Windows, macOS, and Linux, but they do have a steeper learning curve. - NiceGUI: This is a fantastic option if you want your app to run in a web browser by default, which simplifies sharing and access. It also has an option to run as a native-like desktop application. It's easy to use and great for interactive tools and dashboards. Ultimately, Tkinter with CustomTkinter is great for beginners and simple tools. Go with PyQt/PySide6 for complex, high-end desktop applications. And for web-first apps with a native option, NiceGUI is a strong contender. More on reddit.com
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June 25, 2025Videos
29:19
Build A Modern Python GUI Project | Step by Step Tutorial - YouTube
The ultimate introduction to modern GUIs in Python [ with tkinter ]
18:31
Build GUI Apps With Python! - Intro To Tkinter 1 - YouTube
11:12
Modern Graphical User Interfaces in Python - YouTube
20:55
Pythonで作るデスクトップGUIアプリ入門【Tkinter編】 ...
10:06
PythonをGUIで操作すっぺや - YouTube
NiceGUI
nicegui.io
NiceGUI
NiceGUI is an easy-to-use, Python-based UI framework, which shows up in your web browser. You can create buttons, dialogs, Markdown, 3D scenes, plots and much more.
Reddit
reddit.com › r/learnpython › what python guis do you recommend?
r/learnpython on Reddit: What python GUIs do you recommend?
February 23, 2024 -
Hi all! With the recent planned 'sunset' of pySimpleGUI 4 and questionable license for psg 5 which GUI library do you recommend? About my work: I'm a scientist in a field on nanophysics and I have to put many graphs into my programs and prefer GUI building to be the lesser problem;)
Upd: I worked for a year or so with psg but now want to move
Upd2: Big thanks to all of you for the suggestions! If anyone curious, I settled with DearPyGUI as it seems to meet all my needs and isn't (sorry) web-based.
Upd3: Their digital signature is so broken, it required like 30 minutes to tamper their code LOL
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Tkinter: Easy, quick, in standard library. Not too many options, looks awful, cracks at the seam on complex things, documentation is between bad and non-existent. Custom-tkinter (look for it on github) makes it look better. Pyside6/PyQt6: Extremely powerful, has everything and 3 kitchen sinks, looks as good as you want, reliable. Pretty big learning curve, documentation is geared to c++, once you get in the qt boat you stay on the qt boat. html/CSS/Javascript. As complex as you want, good learning opportunity, can look amazing, usable on phone and tablet, final app is easy to distribute and update. Requires a server (that's huge!), need to learn multiple languages and frameworks so big learning curve, cannot center a div :) !
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Flet or Nice GUI. Both allow for web or desktop apps and have chart, diagram, and table widgets built in.
Tutorialspoint
tutorialspoint.com › python › python_gui_programming.htm
Python - GUI Programming
Jython − Jython is a Python port ... many other interfaces available, which you can find them on the net. Tkinter is the standard GUI library for Python....
Python GUIs
pythonguis.com › faq › which python gui library should you use?
Which Python GUI library should you use in 2026?
3 days ago - Compare the best Python GUI libraries and frameworks in 2026 including PyQt6, PySide6, Tkinter, Kivy, wxPython, BeeWare Toga, Streamlit, NiceGUI, Flet, Dear PyGui, and more. Find the right toolkit for desktop, mobile, and embedded GUI development.
Opensource.com
opensource.com › resources › python › gui-frameworks
5 open source Python GUI frameworks | Opensource.com
Tkinter is available under the Python license, on top of the BSD license of Tcl/Tk. WxPython brings the wxWidgets cross-platform GUI library from its native C++ to Python. WxPython looks a little more native than Tkinter across different operating systems because it uses the host system's widgets to construct a GUI.
The Hitchhiker's Guide to Python
docs.python-guide.org › scenarios › gui
GUI Applications — The Hitchhiker's Guide to Python
There’s more information available on the Python Wiki. wxPython is a GUI toolkit for the Python programming language. It allows Python programmers to create programs with a robust, highly functional graphical user interface, simply and easily.
Real Python
realpython.com › pysimplegui-python
PySimpleGUI: The Simple Way to Create a GUI With Python – Real Python
July 9, 2024 - In this step-by-step tutorial, ... and PySimpleGUI. A graphical user interface is an application that has buttons, windows, and lots of other elements that the user can use to interact with your application....
Medium
medium.com › @SrvZ › how-to-make-your-python-gui-look-awesome-9372c42d7df4
How to make your Python GUI look awesome | by Sourav De | Medium
January 7, 2023 - It’s not difficult to build GUI in Python as we have Tkinter built-in module to create simple and functional GUI in minutes.
Real Python
realpython.com › python-gui-tkinter
Python GUI Programming: Your Tkinter Tutorial – Real Python
December 7, 2024 - Tkinter is Python’s standard GUI framework, making it convenient for developing graphical user interfaces. As a cross-platform library, Tkinter ensures your applications appear native across Windows, macOS, and Linux.
Real Python
realpython.com › tutorials › gui
Python GUI Programming – Real Python
Python GUI frameworks help you create desktop applications with graphical user interfaces. Build windows, buttons, menus, and forms with Tkinter for simple tools, PyQt for professional applications, or wxPython for native-looking interfaces.
GeeksforGeeks
geeksforgeeks.org › python › python-gui-tkinter
Python Tkinter - GeeksforGeeks
January 23, 2026 - Tkinter is Python’s built-in library for creating graphical user interfaces (GUIs). It acts as a lightweight wrapper around Tcl/Tk GUI toolkit, offering Python developers a simple and intuitive way to build desktop applications.
Kivy
kivy.org
Kivy: Cross-platform Python Framework for GUI apps Development
Open source Python framework for rapid development of applications that make use of innovative user interfaces, such as multi-touch apps.
CustomTkinter
customtkinter.tomschimansky.com
Official Documentation And Tutorial | CustomTkinter
CustomTkinter is a python desktop UI-library based on Tkinter, which provides modern looking and fully customizable widgets.
BairesDev
bairesdev.com › home › blog › software development
8 Best Python GUI Frameworks
The important thing to notice above is the use of tkinter, which is a library for Python that makes it possible to create user interfaces and full-fledged GUI applications. There are quite a few libraries for the language.
Python GUI
pythongui.org › home
Python GUI
Build Powerful Python GUI Apps for Android, Windows, Linux, and MacOS
Real Python
realpython.com › learning-paths › python-gui-programming
Create Graphical User Interfaces (GUI) (Learning Path) – Real Python
Learning Path ⋅ Skills: Tkinter, PyQt, wxPython, Kivy, GUI Layouts, Event Handling, Database Integration, Thread Management, Mobile App Development, GUI Design · In this learning path, you’ll build graphical user interfaces with Python using multiple frameworks.
Built In
builtin.com › software-engineering-perspectives › python-gui
Top 12 Python GUI Frameworks for Developers | Built In
The graphical user interface (GUI) is one of three main cornerstones of any application. Here are the top Python GUI frameworks for developers.
Pysimplegui
pysimplegui.com
PySimpleGUI
PySimpleGUI creates graphical user interfaces (GUIs) using Python, quickly and easily!