As you are talking about trailing zeros, this is a question about representation as string, you can use

>>> "%.2f" % round(2606.89579999999, 2)
'2606.90'

Or use modern style with format function:

>>> '{:.2f}'.format(round(2606.89579999999, 2))
'2606.90'

and remove point with replace or translate (_ refers to result of previous command in python console):

>>> _.translate(None, '.')
'260690'

Note that rounding is not needed here, as .2f format applies the same rounding:

>>> "%.2f" % 2606.89579999999
'2606.90'

But as you mentioned excel, you probably would opt to roll your own rounding function, or use decimal, as float.round can lead to strange results due to float representation:

>>> round(2.675, 2)
2.67
>>> round(2606.89579999999, 2)
2606.89

With decimal use quantize:

>>> from decimal import *
>>> x = Decimal('2606.8950000000001')
# Decimal('2606.8950000000001')
>>> '{}'.format(x.quantize(Decimal('.01'), rounding=ROUND_HALF_EVEN))
'2606.90'

That, for your original task, becomes:

>>> x = Decimal('2606.8950000000001')
>>> int((x*100).quantize(1, rounding=ROUND_HALF_EVEN))
260690

And the reason of strange rounding comes to the front with Decimal:

>>> x = Decimal(2606.8950000000001)
# Decimal('2606.89499999999998181010596454143524169921875') # internal float repr

Pass the rounded value to int() to get rid of decimal digits:

>>> value = 10.01
>>> int(round(value))
10
>>> value = 10.55
>>> int(round(value))
11