You can wrap the string in a StringIO or BytesIO and pretend it's a file. That should be pretty fast.

from cStringIO import StringIO
# or, in Py3/Py2.6+:
#from io import BytesIO, StringIO

s = StringIO(large_string)
while True:
    chunk = s.read(200)
    if len(chunk) > 0:
        process(chunk)
    if len(chunk) < 200:
        break
Answer from Fred Foo on Stack Overflow
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Mimo
mimo.org › glossary › python › pop()
Python Pop Method: Essential Data Manipulation techniques
Without an argument, the default index is -1, pointing to the last element in the list. ## **When to Use pop() in Python Lists** ### Stack Data Structure A stack is a classic use case for `pop()` because it removes the last added element first (last in, first out).
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W3Schools
w3schools.com › python › ref_list_pop.asp
Python List pop() Method
Remove List Duplicates Reverse ... Plan Python Interview Q&A Python Bootcamp Python Training ... The pop() method removes the element at the specified position....
Discussions

I am new to python how to remove the first character(letter) from a word in python?
See this tutorial for information on how to get substrings from strings in Python. More on reddit.com
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February 2, 2021
python - Equivalent for pop on strings - Stack Overflow
Given a very large string. I would like to process parts of the string in a loop like this: large_string = "foobar..." while large_string: process(large_string.pop(200)) What is a nice and eff... More on stackoverflow.com
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Python Remove last char from string and return it - Stack Overflow
Do you need the shortened string or just the popped character (and the next popped character and the next ...)? ... Strings are "immutable" for good reason: It really saves a lot of headaches, more often than you'd think. It also allows python to be very smart about optimizing their use. More on stackoverflow.com
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python - Remove the first character of a string - Stack Overflow
I would like to remove the first character of a string. For example, my string starts with a : and I want to remove that only. There are several occurrences of : in the string that shouldn't be re... More on stackoverflow.com
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DigitalOcean
digitalocean.com › community › tutorials › pop-python
How to Use `.pop()` in Python Lists and Dictionaries | DigitalOcean
July 24, 2025 - The .pop() method is ideal for implementing stacks (Last-In-First-Out) and queues (First-In-First-Out) in Python. For stacks, you can use list.pop() without an index to remove the last item efficiently.
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Hyperskill
hyperskill.org › university › python › pop-in-python
Pop() in Python
October 14, 2025 - The Python pop() function deletes an element from a list at an index or if no index is specified, the last item. It comes in handy for removing items, from a list without changing the order of elements.
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GeeksforGeeks
geeksforgeeks.org › python › python-list-pop-method
Python List pop() Method - GeeksforGeeks
5 days ago - Explanation: a.pop() removes and returns 20 and returned value is stored in num and used in the expression num * 2. Comment · Python Fundamentals · Introduction1 min read · Input & Output2 min read · Variables4 min read · Operators4 min read · Keywords2 min read · Data Types4 min read · Conditional Statements3 min read · Loops3 min read · Functions4 min read · Python Data Structures · String4 min read ·
Top answer
1 of 5
49

Strings are "immutable" for good reason: It really saves a lot of headaches, more often than you'd think. It also allows python to be very smart about optimizing their use. If you want to process your string in increments, you can pull out part of it with split() or separate it into two parts using indices:

a = "abc"
a, result = a[:-1], a[-1]

This shows that you're splitting your string in two. If you'll be examining every byte of the string, you can iterate over it (in reverse, if you wish):

for result in reversed(a):
    ...

I should add this seems a little contrived: Your string is more likely to have some separator, and then you'll use split:

ans = "foo,blah,etc."
for a in ans.split(","):
    ...
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8

Not only is it the preferred way, it's the only reasonable way. Because strings are immutable, in order to "remove" a char from a string you have to create a new string whenever you want a different string value.

You may be wondering why strings are immutable, given that you have to make a whole new string every time you change a character. After all, C strings are just arrays of characters and are thus mutable, and some languages that support strings more cleanly than C allow mutable strings as well. There are two reasons to have immutable strings: security/safety and performance.

Security is probably the most important reason for strings to be immutable. When strings are immutable, you can't pass a string into some library and then have that string change from under your feet when you don't expect it. You may wonder which library would change string parameters, but if you're shipping code to clients you can't control their versions of the standard library, and malicious clients may change out their standard libraries in order to break your program and find out more about its internals. Immutable objects are also easier to reason about, which is really important when you try to prove that your system is secure against particular threats. This ease of reasoning is especially important for thread safety, since immutable objects are automatically thread-safe.

Performance is surprisingly often better for immutable strings. Whenever you take a slice of a string, the Python runtime only places a view over the original string, so there is no new string allocation. Since strings are immutable, you get copy semantics without actually copying, which is a real performance win.

Eric Lippert explains more about the rationale behind immutable of strings (in C#, not Python) here.

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Medium
medium.com › @pythonchallengers › python-challenge-unveiled-3-exceptional-approaches-to-solve-it-55c0de213f60
Python Challenge: Removes first and last characteres | by Python Challengers | Medium
December 6, 2023 - In this case, the first pop() removes the first character (index 0) from the list, and the second pop() removes the last character from the list. Therefore, the code is removing the first and last characters of the original word.
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Programiz
programiz.com › python-programming › methods › list › pop
Python List pop()
If you need to pop the 4th element, you need to pass 3 to the pop() method. # programming languages list languages = ['Python', 'Java', 'C++', 'Ruby', 'C'] # remove and return the last item print('When index is not passed:')
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freeCodeCamp
freecodecamp.org › news › pop-function-in-python
Pop Function in Python
January 29, 2020 - The pop() method is often used in conjunction with append() to implement basic stack functionality in a Python application.
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Snakify
snakify.org › strings
Strings - Learn Python 3 - Snakify
Method find() searches a substring, passed as an argument, inside the string on which it's called. The function returns the index of the first occurrence of the substring.
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Simplilearn
simplilearn.com › home › resources › software development › pop in python: an introduction to pop function with examples
Pop in Python: An Introduction to Pop Function with Examples
November 13, 2025 - Pop in Python is a pre-defined, in-built function. Learn pop function's ✓ syntax ✓ parameters ✓ examples, and much more in this tutorial. Start learning now!
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Quora
quora.com › What-is-the-pop-method-in-Python-How-useful-are-those
What is the pop() method in Python? How useful are those? - Quora
Answer (1 of 3): pop() method is used to remove or pop out items from a list,dictionary or any such type of Collection. In stack also we make use of pop() method to pop out the last inserted item or the first item present at the top of the stack. In python also pop() method works the same way E...
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W3Schools
w3schools.com › python › ref_dictionary_pop.asp
Python Dictionary pop() Method
Remove List Duplicates Reverse a String Add Two Numbers · Python Examples Python Compiler Python Exercises Python Quiz Python Challenges Python Practice Problems Python Server Python Syllabus Python Study Plan Python Interview Q&A Python Bootcamp Python Training ... car = { "brand": "Ford", "model": "Mustang", "year": 1964 } car.pop("model") print(car) Try it Yourself »
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Python Help
pythonhelp.org › python-lists › how-to-pop-first-element-in-list-python
How to Pop First Element in List Python
October 2, 2023 - This article will show you how to use the pop() function to remove and retrieve the first item in a list in Python, which can be extremely useful when working with various types of data structures like deque, stacks, etc.
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DigitalOcean
digitalocean.com › community › tutorials › python-remove-character-from-string
How to Remove Characters from a String in Python | DigitalOcean
May 31, 2026 - str.replace() returns a copy of the string with each occurrence of the first argument replaced by the second. Pass an empty string as the second argument to delete matches. ... Both a characters are gone; the original s is still 'abc12321cba'. ... Only the first two a characters change. See Python String replace() for more detail.