IMO there might be a problem with the way you are using replace. The syntax for replace is explained. here

string.replace(s, old, new[, maxreplace])

This ipython session might be able to help you.

In [1]: mystring = "whatever"

In [2]: mystring.replace('er', 'u')
Out[2]: 'whatevu'

In [3]: mystring
Out[3]: 'whatever'

basically the pattern you want replaced comes first, followed by the string you want to replace with.

Answer from Anuvrat Parashar on Stack Overflow
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W3Schools
w3schools.com โ€บ python โ€บ ref_string_replace.asp
Python String replace() Method
Remove List Duplicates Reverse ... Study Plan Python Interview Q&A Python Training ... The replace() method replaces a specified phrase with another specified phrase....
Discussions

Python: How can I replace one specific character on a string while leaving the rest of the string as it was?
On July 1st, a change to Reddit's API pricing will come into effect. Several developers of commercial third-party apps have announced that this change will compel them to shut down their apps. At least one accessibility-focused non-commercial third party app will continue to be available free of charge. If you want to express your strong disagreement with the API pricing change or with Reddit's response to the backlash, you may want to consider the following options: Limiting your involvement with Reddit, or Temporarily refraining from using Reddit Cancelling your subscription of Reddit Premium as a way to voice your protest. I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns. More on reddit.com
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October 18, 2023
Python - Replacing letters in a string? - Stack Overflow
I am basically writing a simple function in which the user enters a sentence (strng), a letter (letter) and another letter (replace) to replace the first letter with. Here's what I have: def More on stackoverflow.com
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Replace character in string
Assuming that you're only working with single characters, you can create a dictionary that associates characters with strings. Iterate through the characters, and then join the resulting iterable. def replace_chars(dct, s): return ''.join(dct.get(c, c) for c in s) In the REPL: >>> replace_chars({"A" : "BC", "B" : "CD"}, "AB") 'BCCD' (Challenge: What if you want to replace an arbitrary number of characters? That is, "AB" should be replaced with "C", but if it only finds "A", it should replace with "D") More on reddit.com
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October 31, 2021
How to replace a string that is all the same character at a specific index?
Slice and concatenate. string1 = string1[:-1] + 'b' More on reddit.com
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Real Python
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How to Replace a String in Python โ€“ Real Python
October 22, 2025 - ... To remove part of a string, you can use the .replace() method, specifying the part you want to remove and using an empty string as the replacement. ... You replace a letter in a string by using the .replace() method, where the first argument is the letter you want to replace, and the second argument is the new letter you want to use...
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StrataScratch
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How to Replace a Character in a Python String - StrataScratch
October 18, 2024 - They represent white spaces between the words, which are also treated as characters when converting from a string to a list. ... Weโ€™ll use the list comprehension to get rid of those blank rows because white space is not a letter. In the code below, the list comprehension iterates over the column letter and replaces the blank spaces (' ') with NaN values.
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Mimo
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How to Replace Characters in a String in Python
Replace characters in Python strings with replace() or translate(), including limits and multi-character swaps.
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Spark By {Examples}
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Python Replace Character in String - Spark By {Examples}
May 21, 2024 - How to replace a character in a string in Python? To replace a character in a string using Python, you can utilize the str.replace() method. This method
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PyTutorial
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PyTutorial | Replace Letter in String Python Guide
February 18, 2026 - All specified letters were changed in a single pass. This is much faster than calling replace() multiple times. You can also use maketrans() with two equal-length strings. The first contains characters to find, the second contains their replacements. This is another useful pattern, similar in concept to a Python Letter to Number Conversion Guide.
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freeCodeCamp
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Python string.replace() โ€“ How to Replace a Character in a String
September 1, 2022 - Here's an example that replaces "JavaScript" with "PHP" in a string: str = "I love JavaScript. I prefer JavaScript to Python because JavaScript looks more beautiful" new_str = str.replace("JavaScript", "PHP") print(new_str) # I love PHP.
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Quora
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What's the quickest way to replace a letter in a string in Python? - Quora
Answer: You canโ€™t actually change a letter in a string, a string in Python is immutable, but you can create a new string based in the original : if you want to replace all examples of a letter with another, then thr best way is to use the replace method. [code]>>> orig = โ€˜The_rain_in_spainโ€™ ...
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PyTutorial
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PyTutorial | Replace Letter in String Python | Easy Guide
February 18, 2026 - Here is the basic syntax for the replace() method. # Syntax: string.replace(old, new, count) # old: The substring to find. # new: The substring to replace it with. # count (optional): How many occurrences to replace.
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Scaler
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Replace a Character in a String Python - Scaler Topics
April 20, 2024 - The .replace() method replaces the old character with a new character. We can also use loops to replace a character in a string in Python. The string slicing method can also be used to replace a string in python.
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FavTutor
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Python Replace Character in String | FavTutor
October 6, 2021 - For this approach, you can make use of for loop to iterate through a string and find the given indexes. Later, the slicing method is used to replace the old character with the new character and get the final output.
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iO Flood
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Using Python to Replace Characters in a String
November 23, 2023 - As you can see, the replace() method has replaced โ€˜aโ€™ with โ€˜bโ€™, resulting in the new string โ€œbppleโ€. For more advanced methods, tips, and tricks, read on. ... Python offers an in-built method for replacing characters in a string: the replace() function.
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CodeGenes
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How to Replace a Letter in a String in Python โ€” codegenes.net
In Python, strings are immutable, which means once a string is created, you cannot change its contents directly. When you perform a replacement operation on a string, Python actually creates a new string object with the desired changes.
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GeeksforGeeks
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Python String replace() Method - GeeksforGeeks
October 28, 2024 - Hi Python!". Note: Since replace() creates a new string, the original string remains unchanged. ... count (optional): Specifies the maximum number of replacements to perform. If omitted, all occurrences are replaced. Returns a new string with the specified replacements made. The original string remains unchanged since strings in Python are immutable.
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Initial Commit
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Replace Character in String Python | Python String Replace()
October 26, 2022 - Strings also follow zero-based ... string. For example: ... The replace() string method allows us to replace all occurrences of a specific character old in a python string with another character new....
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Programiz
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Python String replace()
The replace() method returns a copy of the string where the old substring is replaced with the new string.
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Pierian Training
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Python Tutorial: Replace Character in a String - Pierian Training
April 27, 2023 - In this example, we first define a string called `sentence`. We then use the replace() method to replace all occurrences of the letter โ€œoโ€ with the number โ€œ0โ€. The resulting string is stored in a new variable called `new_sentence`. Finally, ...