map( lambda s: s.replace(...), row )

or use a list comprehension

[s.replace(...) for s in row]

Both of these methods are used for substituting values.

From Series.replace docs:

Replace values given in to_replace with value.

From Series.map docs:

Used for substituting each value in a Series with another value, that may be derived from a function, a dict or a Series.

They differ in the following:

1. replace accepts str, regex, list, dict, Series, int, float, or None. map accepts a dict or a Series.
2. They differ in handling null values.
3. replace uses re.sub under the hood.The rules for substitution for re.sub are the same.

Take below example:

In [124]: s = pd.Series([0, 1, 2, 3, 4])    
In [125]: s
Out[125]: 
0    0
1    1
2    2
3    3
4    4
dtype: int64

In [126]: s.replace({0: 5})
Out[126]: 
0    5
1    1
2    2
3    3
4    4
dtype: int64

In [129]: s.map({0: 'kitten', 1: 'puppy'}) 
Out[129]: 
0    kitten
1     puppy
2       NaN
3       NaN
4       NaN
dtype: object

As you can see for s.map method, values that are not found in the dict are converted to NaN, unless the dict has a default value (e.g. defaultdict)

For s.replace, it just replaces the value to be replaced keeping the rest as it is.

I don't know if i correctly understand your question, but you can map the dict values across the columns as follows..

Example DataFrame:

>>> df
     A    B    C    D
0   no   no   no  yes
1  yes  yes  yes   no
2  yes   no  yes   no
3   no  yes   no  yes

Result:

>>> for col in 'ABCD':
     df[col] = df[col].map({'yes':True, 'no':False})

>>> df
       A      B      C      D
0  False  False  False   True
1   True   True   True  False
2   True  False   True  False
3  False   True  False   True

Here is a PSU link that searches and replaces for a certain text element within a given mxd (code sample below).

# Create a MapDocument object referencing the MXD you want to update
mxd = arcpy.mapping.MapDocument(r"C:\GIS\TownCenter_2009.mxd")

# Loop through each text element in the map document
for textElement in arcpy.mapping.ListLayoutElements(mxd, "TEXT_ELEMENT"):

    # Check if the text element contains the out of date text
    if textElement.text == "GIS Services Division 2009":

    # If out of date text is found, replace it with the new text
        textElement.text = "GIS Services Division 2010"