Mayo Clinic
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Steps to keep your mood and motivation steady throughout the year-Seasonal affective disorder (SAD) - Symptoms & causes - Mayo Clinic
December 14, 2021 - Reduced sunlight can cause a drop in serotonin that may trigger depression. Melatonin levels. The change in season can disrupt the balance of the body's level of melatonin, which plays a role in sleep patterns and mood.
Videos
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Seasonal Affective Disorder (SAD) | Causes and treatment - YouTube
2-Minute Neuroscience: Seasonal Affective Disorder - YouTube
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What Causes Seasonal Affective Disorder? The Science of SAD Explained ...
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Why Winter Makes You Sad (Seasonal Affective Disorder Explained) ...
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Seasonal Affective Disorder - Mayo Clinic Health System - YouTube
mental depression that involves presentation of depressive symptoms only during a specific season of the year
Factsheet
Specialty Psychiatry
Specialty Psychiatry
Wikipedia
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Seasonal affective disorder - Wikipedia
1 week ago - Seasonal affective disorder (SAD, colloquially referred to as seasonal depression) is a mood disorder subset in which people who typically have normal mental health throughout most of the year exhibit depressive symptoms at the same time each year. It is commonly, but not always, associated ...
NIMH
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Seasonal Affective Disorder - National Institute of Mental Health (NIMH)
Most research to date has investigated potential causes of winter-pattern SAD because it is more common and easier to study. As a result, less is known about summer-pattern SAD, and more research is needed. Studies indicate that people with SAD, especially winter-pattern SAD, have reduced levels of the brain chemical serotonin, which helps regulate mood. Research also suggests that sunlight affects levels of molecules that help maintain normal serotonin levels.
PubMed Central
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Seasonal Affective Disorder: An Overview of Assessment and Treatment Approaches - PMC
People with seasonal affective disorder have difficulty regulating the neurotransmitter serotonin, a neurotransmitter believed to be responsible for balancing mood [2]. In one study, people with SAD had 5% more SERT, a protein that assists with serotonin transport, in the winter months than in summer [2]. SERT transports serotonin from the synaptic cleft to the presynaptic neuron, so higher SERT levels lead to lower serotonin activity, thus causing depression [2]. Throughout the summer, sunlight generally keeps SERT levels naturally low [2]. But as sunlight diminishes in the fall, a corresponding decrease in serotonin activity also occurs.
Cleveland Clinic
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Seasonal Depression (Seasonal Affective Disorder)
July 14, 2025 - Seasonal depression, or seasonal affective disorder (SAD), is a form of depression triggered by the change of seasons.
American Psychiatric Association
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Psychiatry.org - Seasonal Affective Disorder (SAD)
SAD has been linked to changes in the brain prompted by shorter daylight hours and less sunlight in winter. As seasons change, people experience a shift in their biological internal clock or circadian rhythm that can cause them to be out of ...
Norcalbehavioral
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The Science Behind Seasonal Affective Disorder: Causes and Risk Factors - Behavioral Healthcare Hospitals
March 25, 2025 - Biology plays a critical role in shaping how individuals respond to seasonal changes. Genetics: Research suggests that genetic predisposition may influence a personโs susceptibility to SAD. A family history of depression or mood disorders can increase the likelihood of experiencing symptoms. Hormonal Influence: As sunlight exposure decreases, the body produces more melatonin and less serotonin, affecting sleep patterns and emotional regulation.
NCBI
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Seasonal Affective Disorder - StatPearls - NCBI Bookshelf - NIH
April 20, 2024 - The condition is linked to neurotransmitters like dopamine, norepinephrine, and glutamate, although the exact pathophysiology is unclear.[1][12] Disruptions in the body's circadian rhythm due to reduced sunlight exposure during fall and winter are thought to be involved in the onset of winter-onset ...
CAMH
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Seasonal Affective Disorder (SAD) | CAMH
Seasonal affective disorder is a type of depression that occurs during the same season each year. Researchers think that SAD is caused by changes in the level of exposure to sunlight. Light therapy is the main treatment for SAD.
American Medical Association
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What doctors wish patients knew about seasonal affective disorder | American Medical Association
October 31, 2025 - When the days grow shorter and temperatures drop, millions of people find themselves grappling with the โwinter blues.โ This is known as seasonal affective disorder, which is a form of depression that follows a seasonal pattern. Emerging primarily during the fall and winter months when sunlight exposure decreases and clocks fall back, seasonal affective disorder can take a toll on a personโs daily life.
Kaiser Permanente
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Seasonal Affective Disorder (SAD) | Kaiser Permanente
Lack of light may upset your "biological clock," which controls your sleep-wake pattern and other circadian rhythms. Lack of light may also cause problems with serotonin, a brain chemical that affects mood. Seasonal affective disorder (SAD) can come and go at about the same time each year.