It depends on what you are intending to do with it.
Sets are significantly faster when it comes to determining if an object is present in the set (as in x in s), but its elements are not ordered so you cannot access items by index as you would in a list. Sets are also somewhat slower to iterate over in practice.
You can use the timeit module to see which is faster for your situation.
Answer from Michael Aaron Safyan on Stack OverflowPython Sets vs Lists - Stack Overflow
Why we use SET instead of using array?? , it says both are same but i feel set a little bit uncomfortable? is there any idea of using SET? I want to know some cool fact about using set?
The difference between arrays sets and objects?
Are arrays and lists essentially the same?
It depends on what you are intending to do with it.
Sets are significantly faster when it comes to determining if an object is present in the set (as in x in s), but its elements are not ordered so you cannot access items by index as you would in a list. Sets are also somewhat slower to iterate over in practice.
You can use the timeit module to see which is faster for your situation.
Lists are slightly faster than sets when you just want to iterate over the values.
Sets, however, are significantly faster than lists if you want to check if an item is contained within it. They can only contain unique items though.
It turns out tuples perform in almost exactly the same way as lists, except for their immutability.
Iterating
>>> def iter_test(iterable):
... for i in iterable:
... pass
...
>>> from timeit import timeit
>>> timeit(
... "iter_test(iterable)",
... setup="from __main__ import iter_test; iterable = set(range(10000))",
... number=100000)
12.666952133178711
>>> timeit(
... "iter_test(iterable)",
... setup="from __main__ import iter_test; iterable = list(range(10000))",
... number=100000)
9.917098999023438
>>> timeit(
... "iter_test(iterable)",
... setup="from __main__ import iter_test; iterable = tuple(range(10000))",
... number=100000)
9.865639209747314
Determine if an object is present
>>> def in_test(iterable):
... for i in range(1000):
... if i in iterable:
... pass
...
>>> from timeit import timeit
>>> timeit(
... "in_test(iterable)",
... setup="from __main__ import in_test; iterable = set(range(1000))",
... number=10000)
0.5591847896575928
>>> timeit(
... "in_test(iterable)",
... setup="from __main__ import in_test; iterable = list(range(1000))",
... number=10000)
50.18339991569519
>>> timeit(
... "in_test(iterable)",
... setup="from __main__ import in_test; iterable = tuple(range(1000))",
... number=10000)
51.597304821014404
If not, what are the differences