All answers I could quickly find on this topic involve either the tip Molly gave or using an application (or coding it yourself). For example (I haven't tried this), Close All Windows.

Also, by pressing Ctrl + Shift + Esc you get the Windows Task Manager, where you can see all running applications at once (among other things), select them, and End Task them.

Answer from Adriano Varoli Piazza on Stack Exchange
Discussions

Is there a way to close these at the same time?
If you set combine taskbar buttons to "Always, hide labels", it's possible to close all windows of the same application at the same time. More on reddit.com
๐ŸŒ r/windows
10
8
January 27, 2024
Easy Keyboard Shortcut to actually close a program?
Alt+F4 works for me. More on reddit.com
๐ŸŒ r/windows
13
2
November 12, 2020
Quickly close all windows at once
I deal with personal information and am subject to privacy laws. When someone walks in to my office I need to quickly close all the windows on my computer to ensure no private information is inadvertently revealed. How do I close all windows at once? โ€ฆ More on answers.microsoft.com
๐ŸŒ answers.microsoft.com
5
70
September 27, 2023
How to close all windows at once
ctrl+alt+delete or ctrl+shift+esc which opens the task manager and then you can kill the processes. More on reddit.com
๐ŸŒ r/Windows10
10
1
September 24, 2019
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Reddit
reddit.com โ€บ r/windows10 โ€บ how to close all windows at once
r/Windows10 on Reddit: How to close all windows at once
September 24, 2019 -

I selected 100 over videos and pressed enter. I thought it would start from beginning and play it from start to end. Similar to what i would do if i opened multiple images.

Well i selected 100 over videos and pressed enter. Now my computer is stuck because there are too many videos opening at once and its too slow. Even pressing control alt del is really slow. I want to kill all processes and kill anything else that is coming up as well. I closed all windows using task bar but it only killed the ones open and not the ones that were opening.

Now my computer is slowly filling up with the prompt "The application is not responding. This program may respond again if you wait. Do you want to end this process?" This is just one of the prompts for my 100 over prompts which will come later.

If this happens again, is there a command i can press on my computer to cancel everything and freeze all processes from continuing without shutting down my computer? Thanks

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Quora
quora.com โ€บ Is-there-a-key-or-series-of-keys-that-closes-all-currently-opened-windows-on-a-windows-computer
Is there a key or series of keys that closes all currently opened windows on a windows computer? - Quora
Answer (1 of 5): Open task manager (right-click the task bar) Hold down the shift key and down arrow key to highlight all open windows. End task (this will close all windows) One click of mouse to close all programs and turn off the computer. I created an icon when I click on it the computer s...
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Ntwind
ntwind.com โ€บ software โ€บ closeall.html
Close All Windows at Once with Just a Single Click โ€“ Super Fast & Easy App - NTWind Software
You can specify /NOUI command line switch to run CloseAll in silent mode and close all windows without any UI interaction. Just open CloseAll shortcut properties and add /NOUI to the โ€œTargetโ€ location:
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Wikihow
wikihow.com โ€บ computers and electronics โ€บ basic computer skills โ€บ how to close windows on pc, mac, android, and iphone
How to Close Windows on PC, Mac, Android, and iPhone
August 22, 2025 - If you're using a browser like Chrome or Edge, this keyboard shortcut will close the active browsing tab without closing the browser application. Click Ctrl+โ‡ง Shift+W to close all of the tabs in a window, effectively closing the entire window. ...
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Into Windows
intowindows.com โ€บ home โ€บ windows 10 โ€บ fastest way to close all programs and windows using alt + f4 keys
Fastest Way To Close All Programs and Windows In Windows 10/11
November 30, 2023 - Simply press the Enter key to shut down your PC. Hope this tip helps you quickly close all windows and programs. Good luck! 2 Ways To Close Programs From Alt + Tab Screen In Windows 10
Find elsewhere
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Quikteks
quikteks.com โ€บ blog โ€บ 163-weekly-tip-quickly-close-all-windows-programs
Quickly Close All Windows Programs - Quikteks Tech Support
March 2, 2023 - Press Alt + E to close all the programs. Finish off by closing the Windows Task Manager by clicking the X in the top right-hand corner (or you can do Alt + F /down arrow and select the Exit Task Manager option).
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CNET
cnet.com โ€บ tech โ€บ computing โ€บ the fastest way to close all running programs in windows
The fastest way to close all running programs in Windows - CNET
October 27, 2012 - Press the down arrow, and then ... in the window. When they're all selected, press Alt-E, then Alt-F, and finally x to close Task Manager. For those of you keeping score at home, that's seven steps that can be accomplished in less than 10 seconds.
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Lifewire
lifewire.com โ€บ close-open-windows-using-shortcut-keys-3506953
The Fastest Way to Close Unnecessary Windows on Your Desktop
November 13, 2020 - Another option is to select the window you want to close and then press Fn+Alt+F4. You'll probably need two hands for this one. Although the shortcut is officially listed as Alt+F4, you must hold down the Function (Fn) key for it to work. The Ctrl+W shortcut only closes the current file you're working on, but it leaves the program open. This feature can be handy if you want to leave the desktop program open but get rid of all the files you're working on in quick succession.
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Microsoft Support
support.microsoft.com โ€บ en-us โ€บ windows โ€บ keyboard-shortcuts-in-windows-dcc61a57-8ff0-cffe-9796-cb9706c75eec
Keyboard shortcuts in Windows - Microsoft Support
This article lists the default Windows keyboard shortcuts. ... Use the following shortcuts with the Copilot key. Tip: To customize what happens when you press the Copilot key ยท , go to Settings > Personalization > Text input > Customize Copilot key on keyboard. Use the following list of shortcuts to edit text more quickly and efficiently. Use the following keyboard shortcuts to efficiently open, close, navigate, and do other tasks across the Windows desktop environment.
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Sivo
hub.sivo.it.com โ€บ home โ€บ windows shortcuts โ€บ what is the shortcut to close all windows in windows 10?
What is the Shortcut to Close All Windows in Windows 10? | Windows Shortcuts โ€“ Sivo
December 3, 2025 - While there isn't a single universal keyboard shortcut to instantly close all open application windows in Windows 10 with one press, there are several highly efficient methods and shortcuts to quickly close multiple windows or entire programs.
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Reddit
reddit.com โ€บ r/windows โ€บ is there a way to close these at the same time?
r/windows on Reddit: Is there a way to close these at the same time?
January 27, 2024 - Is there a button that closes out all windows at the same time? Tired of closing them all one at a time. ... OpenTTD discussion, strategy, and banter. We also run a suite of community servers! ... This subreddit hosts cheats for the mobile game The Battle Cats. Please DO NOT post cheats you find. Please read the pinned post for more information plus the reason you're probably here. ... Welcome to the largest community for Microsoft Windows 10, the world's most popular computer operating system!
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Windows 10 Forums
tenforums.com โ€บ general-support โ€บ 122431-close-all-open-windows-one-click.html
Close all open windows with one click. Solved - Windows 10 Forums
November 27, 2018 - If there are unsaved documents in use there will always require at least one extra click to either save or lose that data, usually even in a power off choice. The one sure way to close all without a click is holding down the On|Off switch on the computer case for 6 to 10 seconds, a sure way ...
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Reddit
reddit.com โ€บ r/windows โ€บ easy keyboard shortcut to actually close a program?
Easy Keyboard Shortcut to actually close a program? : r/windows
November 12, 2020 - alt+f4 WILL close the entire program, not just "one window from that program"...only time it doesn't is if there are multiple copies of that same program open simultaneously (eg: 2 copies of notepad running, or 2 copies of paint or whatever, then it ill close only the currently active one), ...
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Digital Citizen
digitalcitizen.life โ€บ close-apps-windows-10
8 ways to close apps in Windows 10 like a Pro | Digital Citizen
October 5, 2025 - Close an app from its taskbar menu If more windows of the same app are open, the option at the bottom is called "Close all windows" instead. Clicking or tapping on it closes all the instances of an app running on your Windows 10 computer or device.
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Ova
ova.it.com โ€บ home โ€บ windows shortcuts โ€บ what is the shortcut to close all windows in windows 10?
What is the Shortcut to Close All Windows in Windows 10? โ€“ Ova
December 3, 2025 - While there isn't a single universal keyboard shortcut to instantly close all open application windows in Windows 10 with one press, there are several highly efficient methods and shortcuts to quickly close multiple windows or entire programs.
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PassFab
pdnob.com โ€บ windows-shortcuts โ€บ close-window-shortcut.html
10 close window shortcut you should know
2 weeks ago - The software can be brought to the foreground of the screen without being intrusive using a hotkey or a mouse. Launch the PDNob Shortcut Software. Press middle mouse button to activate the panel. You will see a list of actions to perform. ... Now you will see Close Window icon, Click the Close Window Icon and the active window will be closed. With your mouse, keyboard, or touchscreen, Windows 10 provides you with a number of alternatives for closing programs.