I'm afraid it's not possible without twisting NumPy's arm a lot.

See, the idea behind NumPy is to provide homogeneous arrays, that is, arrays of elements that all have the same type. This type can be simple (int, float...) or more complicated ([('',int),('',float),('',"|S10")]), but in any case, all the elements have the same type. That permits some very efficient memory layout.

So, inherently, a structured array requires the fields (the individual subblocks) to have the same size no matter the position. Examine the following:

>>> np.zeros(3,dtype=[('a',(int,3)),('b',(float,5))])

It defines an array with three elements; each element is composed of two sub-blocks, a and b; a is a block of three ints, b a block of five floats. But once you define the initial size of the blocks in the dtype, you're stuck with that (well, you can always switch, but that's another story).

There's a workaround: using a dtype=object. That way, you're constructing an array of heterogeneous items, like an array of lists of different sizes. But you lose a lot of NumPy power that way. Still, an example:

>>> x=np.zeros(3, dtype=[('a',object), ('b',object)])
>>> x['a'][0] = [1,2,3,4]
>>> x['b'][-1] = "ABCDEF"
>>> print x
[([1, 2, 3, 4], 0) (0, 0) (0, 'ABCD')]

So, we just constructed an array of... objects. I put a list somewhere, a string elsewhere, and it works. You could follow the same example to build an array like you want:

blob = np.array([(a,b,c)],dtype=[('a',object),('b',object),('c',object)])

but then, you should really think twice whether it's really a mean to your end, another structure would probably be more efficient.

A side note: please pay attention to the [(a,b,c)] part of the expression above: notice the ()? You're basically telling NumPy to construct an array of 1 element, composed of three sub-elements (one for each of your a,b,c), each sub-element being an object. If you don't put the (), NumPy will whine a lot.

And a last comment: if you access your fields like blob['a'], you'll get an array of size (1,) and dtype=object: just use blob['a'].item() to get back your original (6,) int array.