Postpartum thyroiditis can occur in about 5% of women, with higher incidence in those with TPOAb during pregnancy.1 The TSH and free thyroxine levels of women with subclinical hypothyroidism should be measured six weeks postpartum.1 If symptoms of hyper- or hypothyroidism are noted, referral to a specialist should be considered.

May 15, 2017 - BACKGROUND Overt hypothyroidism occurs when the TSH in increased and the T4 level is low. Subclinical hypothyroidism is defined by an increased TSH but a normal T4. It is clear that overt hypothyroidism should be treated, especially when diagnosed during pregnancy in the mother.

Observational studies spanning almost three decades suggest that subclinical thyroid disease during pregnancy is associated with adverse outcomes.1–5 In 1999, interest in undiagnosed maternal thyroid dysfunction was heightened by studies suggesting an association between subclinical thyroid hypofunction and impaired fetal neuropsychological development.6,7 In one report, children of women whose serum thyrotropin levels during pregnancy were greater than the 98th percentile had a lower IQ than children of matched controls who had a normal thyrotropin level.6 In another study, children whose m

September 4, 2025 - Subclinical hypothyroidism happens when you have elevated thyroid-stimulating hormone (TSH) levels with normal thyroxine levels. It usually doesn’t cause symptoms, and it may or may not require treatment.

August 24, 2023 - It doesn’t usually cause symptoms, and it’s unclear how or if it affects you or your baby. ... Subclinical hypothyroidism in pregnancy happens when thyroid blood tests shows that you have elevated thyroid stimulating hormone (TSH) levels but normal free thyroxine (T4) levels.

March 30, 2020 - Subclinical hypothyroidism is defined as an elevated serum TSH level in the presence of a normal free T4 level and is found in 2% to 5% of otherwise healthy pregnant women. Subclinical hypothyroidism is unlikely to progress to overt hypothyroidism during pregnancy.

May 1, 2024 - In the only study in this section that evaluated preconception TSH levels to define SCH, Li et al. (55) retrospectively evaluated over 50,000 women with preconception TSH levels drawn from a large Chinese study. Subclinical hypothyroidism was not associated with preterm delivery, pregnancy loss, or large for gestational age births.

Subclinical hypothyroidism is defined as serum TSH above the reference range, and FT4 within the normal ... Overt hypothyroidism is uncommon in pregnancy as it is associated with anovulation and increased rates of

The onset of pregnancy places additional stress of the thyroid gland, which must produce additional thyroid hormones to support the developing foetus. Hypothyroidism, including subclinical hypothyroidism (SCH), may appear de novo at this time, or existing thyroid disease may become more severe.

June 1, 2018 - Subclinical hypothyroidism (SCH), a mild form of hypothyroidism defined as elevated TSH with normal free thyroxine levels, is a common diagnosis among women of reproductive age. In some, but not all, studies, it has been associated with infertility, an increased risk of adverse pregnancy and neonatal outcomes, and possibly with an increased risk of neurocognitive deficits in offspring.

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Hypothyroidism during pregnancy is usually asymptomatic, especially when subclinical. Signs and symptoms which suggest hypothyroidism include inappropriate weight gain, cold intolerance, dry skin and delayed relaxation of deep tendon reflexes.

November 11, 2015 - HYPOTHYROIDISM Should women with subclinical hypothyroidism receive thyroid hormone replacement prior to and during pregnancy? ... Overt hypothyroidism occurs when the TSH level is increased and the free thyroxine level (FT4) is low. This can cause severe symptoms and is associated with an increased incidence of infertility, miscarriage and other adverse outcomes in those women who are trying to conceive or those who are already pregnant.

Conclusions: SCH during pregnancy is associated with multiple adverse maternal and neonatal outcomes. The value of levothyroxine therapy in preventing these adverse outcomes remains uncertain. Subclinical hypothyroidism (SCH) is defined as an elevated thyrotropin (TSH) concentration with normal serum levels of thyroxine (T4).

In addition to an increase level of TSH above 2.5 mU/L during the first trimester, and above 3 mU/L in the second and third trimester, a decrease fT4 concentration (also using reference range for pregnant women) will help clinicians diagnose overt hypothyroidism during pregnancy. Pregnant women with subclinical hypothyroidism will have an elevated trimester-specific serum TSH level but a normal free T4 concentration.

February 15, 2014 - In iodine-sufficient regions, the most common causes are autoimmune thyroiditis and iatrogenic hypothyroidism after treatment for hyperthyroidism.11 Symptoms such as fatigue, weight gain, decreased exercise capacity, and constipation are often ...

February 1, 2019 - Subclinical hypothyroidism (SCH) is defined as an elevated thyroid-stimulating hormone (TSH) concentration in combination with normal concentration of free thyroxine (T4). Systematic review and meta-analysis shows that thyroxine replacement in non-pregnant adults with SCH confers no benefit in either thyroid-related symptoms or quality of life. In pregnancy, the definition of SCH requires gestation-specific reference intervals for TSH and T4, or a TSH between 4.0 and 10.0mU/L.

June 1, 2014 - This guideline has been produced as the official statement of the European Thyroid Association guideline committee. Subclinical hypothyroidism (SCH) in pregnancy is defined as a thyroid-stimulating hormone (TSH) level above the pregnancy-related reference range with a normal serum thyroxine ...

Find guidance for treating patients with subclinical hypothyroidism in conception and pregnancy