September 4, 2025 - Subclinical hypothyroidism happens when you have elevated thyroid-stimulating hormone (TSH) levels with normal thyroxine levels. It usually doesn’t cause symptoms, and it may or may not require treatment.

February 1, 2019 - Tiredness was more common in ... reported symptoms include dry skin, cognitive slowing, poor memory, muscle weakness, cold intolerance, constipation, puffy eyes, and hoarseness.13...

May 15, 2021 - Clinical hypothyroidism affects one in 300 people in the United States, with a higher prevalence among female and older patients. Symptoms range from minimal to life-threatening (myxedema coma); more common symptoms include cold intolerance, fatigue, weight gain, dry skin, constipation, and ...

September 11, 2025 - Hypothyroidism is when your thyroid gland doesn’t make enough hormone. It can make you feel tired or gain weight unexpectedly. Hormone replacement therapy can help.

March 12, 2025 - Read Hypothyroid signs and symptoms for a fuller list. Because subclinical hypothyroidism can be asymptomatic, a blood test is essential to confirm a diagnosis.

August 9, 2023 - The decision to treat subclinical hypothyroidism in children remains a matter of debate. Management should take into account TSH level and the cause of thyroid dysfunction. Children with TSH >10 ulU/L should be treated whatever the cause, while children with TSH between 5-10 ulUL are treated on an individual basis. Treatment should be recommended in children with a goitre, anti-thyroid autoantibodies and hypothyroid signs or symptoms.

December 10, 2022 - Understand what happens when your thyroid is underactive and learn about treatment for this condition.

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Subclinical hypothyroidism is diagnosed when you have: No symptoms or mild symptoms of hypothyroidism.

February 2, 2023 - Subclinical hypothyroidism most of the times has no symptoms. This is especially true when TSH levels are only mildly elevated.

July 9, 2019 - This JAMA Patient Page describes subclinical hypothyroidism and its causes, symptoms, and treatment.

February 15, 2024 - Subclinical hypothyroidism characteristically presents with normal thyroxine (T4) levels and elevated thyroid stimulating hormone (TSH) levels.[1] Minor fluctuations in T4 levels result in considerably larger changes in TSH levels.[2] Although TSH levels exhibit wide variability across the ...

Learn about subclinical (borderline) thyroid conditions

October 23, 2025 - Symptoms of hypothyroidism can be mistaken for the similar symptoms of sex hormone imbalance. Women with mild and moderate symptoms may suffer from subclinical hypothyroidism, which means that even though they experience symptoms of low thyroid, their levels of thyroid hormone still register ...

Large-scale, government-sponsored, ... presence of symptoms, age, and associated medical conditions. ... On completion of this article you should be able to: (1) diagnose and interpret the meaning and clinical importance of subclinical hypothyroidism, (2) assess possible ...

October 21, 2025 - Fatigue, weight gain, hair loss, skin changes — do any of these symptoms sound familiar? Maybe something feels “off” in your body, yet your healthcare practitioner said that your thyroid levels are fine and everything is functioning normally.

February 15, 1998 - Dry skin, cold intolerance and easy fatigability were significantly more common in the patients with raised TSH levels, and these symptoms improved after treatment with thyroid hormone. In another study11 of 69 female patients with subclinical hypothyroidism, a clinical index based on symptoms and physical signs was shown to be more abnormal in patients with higher TSH levels, even though all patients had normal serum levels of T4 and free T4.

December 17, 2025 - Joint and muscle-related problems are not as common as some of the other symptoms listed here but, when they are present, they are often very difficult to treat and require higher doses of specific thyroid medications like SR T3 and liothyronine. ... Thyroid hormone impacts neurotransmitter levels like serotonin which have a downstream effect on behavior. These imbalances can be so strong that they may even lead to a change in personality (hypothyroid patients are more likely to have type D personality disorders) and may even cause psychiatric conditions like bipolar disorder.

October 10, 2022 - Subclinical hypothyroidism involves high levels of thyroid-stimulating hormone and typical thyroxine levels in the blood. This may be due to an autoimmune disease, a medication, or thyroid surgery. People with this condition may not experience symptoms.

June 28, 2024 - In the elderly a diagnosis of hypothyroidism may be delayed by wrongly attributing the symptoms of, for example, fatigue and constipation to ageing. Clinical manifestations can be explained by assuming that a low T4 level, although inside the normal range, may represent a significant decrease from their previous normal and is therefore low for this particular patient. Some studies have suggested that if symptoms are present in subclinical hypothyroidism then treatment with thyroxine will lead to resolution.