British Thyroid Foundation
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Subclinical thyroid disease
Learn about subclinical (borderline) thyroid conditions
Women's Health Network
womenshealthnetwork.com › home › thyroid health › resolving subclinical hypothyroidism symptoms
Subclinical Hypothyroidism Symptoms - Women's Health Network
October 21, 2025 - Fatigue, weight gain, hair loss, skin changes — do any of these symptoms sound familiar? Maybe something feels “off” in your body, yet your healthcare practitioner said that your thyroid levels are fine and everything is functioning normally. How can both things be true? Subclinical hypothyroidism refers to abnormally low thyroid function.
Videos
People with hypothyroidism have specific symptoms, including ...
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15 Signs of HYPOTHYROIDISM You Can See: Doctor Explains - YouTube
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Subclinical Hypothyroidism | Subclinical Hypothyroidism Symptoms ...
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Subclinical hypothyroid, and how it affects the body in perimenopause ...
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Does Subclinical Hypothyroidism Add on Symptoms? - YouTube
Subclinical Hypothyroidism
You’re going to get a lot of bad advice on this sub. But yes, retesting in a month or two is good medical advice before starting a life long medication that may or may not help with your symptoms. Hypothyroid symptoms look like a lot of other disorders. Don’t go doctor shopping because your first one didn’t push pills on you after one borderline TSH test. More on reddit.com
Subclinical hypothyroidism overdiagnosis and treatment
Subclinical hypothyroidism is a difficult topic because is has two categories of symptoms that can occur: Symptoms that can be easily and precisely measured (female infertility, miscarriage, deterioration of cholesterol) and symptoms that are non-specific and not easily measured (anhedonia, fatigue, depression, hair loss, anxiety). Infertility and miscarriages are easily measured and as a consequence most women will get treated if their TSH is above 2.5, certainly if it's above 5. On the other hand, fatigue, depression and anxiety are common, very non-specific and hard to measure objectively. What's more, levothyroxine tends to have a narrow therapeutic index (in most patients, not in all) and if you overdose the patient by a few mcgs she may be just as or even more anxious and fatigued (while mild overdoses on the other hand do not increase the risk of miscarriage, infertility or bad cholesterol), and patient A will do fine at a TSH level that may be too high for patient B but too low for patient C. This makes for very messy and contradictory clinical research and vague guidelines (much less so on the matter of pregnant women, of course). As a consequence, the same doctor who aggressively treats a woman for a TSH of 2.6 if she wants to get pregnant may scoff at the idea of treating someone with a TSH of 8 despite the latter's complaints that she can barely get out of bed and that half her eyebrows have fallen out. From the patients' perspective, this is very unsatisfactory and makes no sense. There's no reason to assume that hard-to-measure symptoms only occur at much higher TSH levels than easy-to-measure symptoms. More practically, many endos take an unexplained elevation of LDL cholesterol and the elevation of TPO/TG antibodies as an argument for treatment, as both make it much more likely that high-in-range or mildly elevated TSH indicates actual thyroid dysfunction. On a side note, the symptoms of iron deficiency (with or without anemia) broadly overlap with the symptoms of thyroid dysfunction, and according to newer studies, iron deficiency affects approximately 20-40% of the pre-menopausal female population, so it may be useful to give a patient complaining of non-specific symptoms iron for a few months unless their ferritin is actually high. More on reddit.com
For those with subclinical hypothyroidism but who are symptomatic, what physical symptoms were alleviated by taking levothyroxine?
I'm subclinical but symptomatic and have been taking Levo for almost a year. I managed to lose weight, even if very slow, the brain fog is much better as is the tiredness. My hair has grown a lot, which it hadn't in a long time. Mood swings have gone down considerably. I feel overall much more like myself again. Edit Sorry, just reread and you wanted unusual symptoms... I used to get ice cold hands and feet, which is unusual because I don't get easily cold. It got so far I bought rechargeable heated gloves. Last winter was the first one in years without those cold spells. I also get extremely itchy skin between my fingers. This symptom has gone down considerably. Same with itchy scalp. More on reddit.com
Is Subclinical Hypothyroidism real or are folks getting misdiagnosed?
I’m here from the perspective of someone trying to conceive, my periods are irregular and when I did have a positive pregnancy test it ended very quickly in an early miscarriage. When my TSH was 5.23, my T4 was slightly below normal ranges; but because of opinions shared in videos and articles like these about TSH must be >10 for treatment, I’ve never been able to access medication. These studies mostly focus on the treatment of older age groups, and it’s worth noticing that some like the BMJ specifically say that pregnant people or people TTC are excluded from the recommendations not to treat SCH. If something can have a big enough impact on your health to affect menstrual cycles or fertility - why is it so hard to believe it might also be impacting other areas of my health? More on reddit.com
Cleveland Clinic Journal of Medicine
ccjm.org › content › 86 › 2 › 101
Subclinical hypothyroidism: When to treat | Cleveland Clinic Journal of Medicine
February 1, 2019 - The risk of progression to clinical disease is higher in patients with thyroid peroxidase antibody, reported as 4.3% per year compared with 2.6% per year in those without this antibody.20,21 In one study, the risk of developing overt hypothyroidism in those with subclinical hypothyroidism increased from 1% to 4% with doubling of the TSH.21 Other risk factors for progression to hypothyroidism include female sex, older age, goiter, neck irradiation or radioactive iodine exposure, and high iodine intake.18,22
NCBI
ncbi.nlm.nih.gov › books › NBK536970
Subclinical Hypothyroidism - StatPearls - NCBI Bookshelf
February 15, 2024 - Subclinical hypothyroidism characteristically presents with normal thyroxine (T4) levels and elevated thyroid stimulating hormone (TSH) levels.[1] Minor fluctuations in T4 levels result in considerably larger changes in TSH levels.[2] Although TSH levels exhibit wide variability across the ...
Thyroid UK -
thyroiduk.org › home › if you are hypothyroid › about hypothyroidism › subclinical hypothyroidism
Subclinical Hypothyroidism - Thyroid UK
March 12, 2025 - We are aware that some women have been diagnosed with subclinical hypothyroidism at a health check appointment and even though they have no symptoms, have been prescribed levothyroxine which then makes them thyrotoxic – possibly because levothyroxine is not actually needed due to having no symptoms.
American Society for Reproductive Medicine
asrm.org › home › practice guidance › practice committee documents › subclinical hypothyroidism in the infertile female population: a guideline (2024)
Subclinical hypothyroidism in the infertile female population: a guideline (2024) | American Society for Reproductive Medicine | ASRM
May 1, 2024 - Subclinical hypothyroidism is diagnosed as a TSH concentration above the upper limit of the normal range and a serumfree thyroxine (T4) concentration within the normal range. However, this designation only applies when thyroid function has been stable for weeks, the hypothalamic-pituitarythyroid axis is normal, and there is no recent or ongoing severe illness (15).
GoodRx
goodrx.com › goodrx health › health conditions › hypothyroidism: symptoms, causes, and treatments › 10 hypothyroidism symptoms in women
10 Hypothyroidism Symptoms in Women - GoodRx
Clinical and biochemical features of muscle dysfunction in subclinical hypothyroidism. The Journal of Clinical Endocrinology & Metabolism. National Institute of Diabetes and Digestive and Kidney Diseases. (2021). Hypothyroidism (underactive thyroid). National Institutes of Health. Oppo, A., et al. (2011). Effects of hyperthyroidism, hypothyroidism, and thyroid autoimmunity on female sexual function.
Published February 21, 2025
WebMD
webmd.com › women's health › reference
Hypothyroidism (Underactive Thyroid): Symptoms, Causes, Tests, Treatments
January 13, 2025 - About 3%-20% of people may develop subclinical hypothyroidism. You may be more likely to develop if you’re a woman or person assigned female at birth (AFAB), over 60, or have type 2 diabetes. You may not have symptoms and may not need treatment, but your doctor will want to monitor your thyroid ...
Mount Sinai
mountsinai.org › health-library › report › hypothyroidism
Hypothyroidism Information | Mount Sinai - New York
Vague symptoms suggesting low metabolism, such as dry skin, fatigue, slight anemia, constipation, depression, and apathy should not be treated indiscriminately with thyroid hormone. Some patients with severe depression are treated with thyroid hormone even though their thyroid blood tests are ...
UpToDate
uptodate.com › contents › subclinical-hypothyroidism-in-nonpregnant-adults
Subclinical hypothyroidism in nonpregnant adults
UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide.
Gdatf
gdatf.org › home › bulletins › other topics › diagnosis and treatment of subclinical hypothyroidism
Diagnosis and Treatment of Subclinical Hypothyroidism | Graves' Disease and Thyroid Foundation
August 18, 2021 - One may present with mild non-specific symptoms of hypothyroidism, such as fatigue, constipation and depression. A mild thyroid gland enlargement or goiter may be seen. In some studies treatment with thyroid hormone was associated with a significant decrease in goiter in cases of subclinical ...
Merck Manual
merckmanuals.com › professional › endocrine and metabolic disorders › thyroid disorders › hypothyroidism
Hypothyroidism - Endocrine and Metabolic Disorders - Merck Manual Professional Edition
June 5, 2024 - Subclinical hypothyroidism is elevated serum TSH in patients with absent or minimal symptoms of hypothyroidism and normal serum levels of free thyroxine (T4). Subclinical thyroid dysfunction is relatively common; it occurs in approximately 15% of older females and 10% of older males (1), particularly in those with underlying Hashimoto thyroiditis.