I found a complete answer at Iterators and Generators (Although it is for TypeScript, this is the same for JavaScript too)

Both for..of and for..in statements iterate over lists; the values iterated on are different though, for..in returns a list of keys on the object being iterated, whereas for..of returns a list of values of the numeric properties of the object being iterated.

Here is an example that demonstrates this distinction:

let list = [4, 5, 6];

for (let i in list) {
   console.log(i); // "0", "1", "2",
}

for (let i of list) {
   console.log(i); // 4, 5, 6
}

Another distinction is that for..in operates on any object; it serves as a way to inspect properties on this object. for..of on the other hand, is mainly interested in values of iterable objects. Built-in objects like Map and Set implement Symbol.iterator property allowing access to stored values.

let pets = new Set(["Cat", "Dog", "Hamster"]);
pets["species"] = "mammals";

for (let pet in pets) {
   console.log(pet); // "species"
}

for (let pet of pets) {
    console.log(pet); // "Cat", "Dog", "Hamster"
}