Use the m.2_0 slot as that should be directly connected to CPU. Second m.2 tends to be connected through chipset, hence why Sata 5/6 might be disabled if you use it. Please refer to the motherboard user manual to help determine this info. Answer from MonopolyMeal on reddit.com
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Asus
asus.com › motherboards / components › motherboards › asus prime motherboards › prime x570-p
PRIME X570-P|Motherboards|ASUS USA
Next-gen connectivity: Supreme flexibility with PCIe 4.0, dual M.2, USB 3.2 Gen 2 ports · Aura Sync RGB header: Synchronize RGB header with a vast portfolio of compatible PC gear, including next-gen addressable RGB strips ... Dressed in a professional attire, the Prime X570 series cater to users with serious pursuits in mind, who prefer to put their Ryzen™ processors to more productive use.
Discussions

Asus X570 pro 2nd m.2 nvme slot - Internal Hardware
Asus X570 pro 2nd m.2 nvme slot - posted in Internal Hardware: Asus X570 pro 2nd m.2 nvme slot. I filled up m.2 1 next to chipset. This is right where my 3070 is. Running fast even though gen 3. There is an lower m.2 gen 2 nvme slot 2nd slot that acording to manual will run at gen 4x4 speeds. More on bleepingcomputer.com
🌐 bleepingcomputer.com
May 18, 2026
Asus prime x570-P compatibility settings with 2700x and hyper m.2 adapter cards
And 1 Samsung 980 evo cdeive in motherboard slot. I'm confused that should I go for Ryzen 2700x and hyper 3rd gen adpater card or Ryzen 3600 hyper 4th gen cards. To fulfill my task. To get pcie 3x16 or pcie4x16 lanes work. I am confused to decide my final combination to decide the final build. There are following doubts and need clarifications opinions and advice to clarify my doubts Q1 does Asus prime x570... More on forums.tomshardware.com
🌐 forums.tomshardware.com
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January 6, 2021
Asus Prime X570 Pro, M.2 SSD Install questions! Pls HALP!
Hey guys! (and gals) So I've got the WD Black 850x that I want to make my main drive for gaming... My old drive is the WD550sn. I know that there are two spots for NVME on X570 Prime Pro, one with the Heat Sink and one closer to the CPU without heatsink. I purchased the 850x without heat sink... More on forums.tomshardware.com
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October 14, 2023
2nd m.2 nvme on asus x570 pro mobo
Hi, I have a decent build with a 3070, 5600x on an asus prime x570 pro. For boot drive, have an 1TB inland for os and such and has worked fine, gen pcie 3.0. It's full, so I'm looking to add a 2nd m.2 to the 2nd m.2 slot on the board. This will work of chipset and use some of the lanes. More on forums.tomshardware.com
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December 16, 2021
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Linus Tech Tips
linustechtips.com › computer hardware › cpus, motherboards, and memory
Asus prime x570-p m.2 slots - CPUs, Motherboards, and Memory - Linus Tech Tips
June 21, 2020 - All the parts (bar the psu) arrived for my second build today, and I have assembled everything and installed into the case. Having set everything up in the case I’ve just noticed that my 500gb 970 evo is in m.2 slot 2. (Below the pcie slots) ...
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BleepingComputer
bleepingcomputer.com › bleepingcomputer forums › hardware › internal hardware
Asus X570 pro 2nd m.2 nvme slot - Internal Hardware
May 18, 2026 - I-7 ASUS ROG Rampage II Extreme / ASUS TUF Gaming F17 / I-7 4770K ASUS ROG Maximus VI Extreme / i-7 14700KF ASUS Prime 790-P WIFI ... As far as I can tell, when fitted with a R5-5600X CPU, both the M.2 slots should both be capable of PCIe 4.0 x4 operation, with a graphics card installed.
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LDLC
ldlc.com › computing › components › motherboard › asus prime x570-p
ASUS PRIME X570-P - Motherboard - LDLC | Holy Moley
With two 4x PCIe 4.0 M.2 slots, the ASUS PRIME X570-P motherboard supports up to two NVMe SSDs to boost the performance of your gaming PC.
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Tom's Hardware Forum
forums.tomshardware.com › home › motherboards
Question - Asus prime x570-P compatibility settings with 2700x and hyper m.2 adapter cards | Tom's Hardware Forum
January 6, 2021 - As specification says https://www.asus.com/Motherboards-Components/Motherboards/All-series/PRIME-X570-P-CSM/techspec 3rd Gen AMD Ryzen™ Processors - 1 x PCIe 4.0 x16 slot (at x16 mode) 2nd Gen AMD Ryzen™ Processors - 1 x PCIe 3.0 x16 slot (at x16 mode) 2nd and 1st Gen AMD Ryzen™ with ...
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Asus
asus.com › motherboards / components › motherboards › asus prime motherboards › prime x570-p
PRIME X570-P - Tech Specs|Motherboards|ASUS USA
AMD Ryzen™ 5000 Series/ 3000 Series Desktop Processors : ,AMD Ryzen™ 5000 G-Series/ 4000 G-Series/ 3000 G-Series/ 2000 Series/ 2000 G-Series Desktop Processors : ,1 x M.2_1 socket 3, with M Key, Type 2242/2260/2280 (PCIE 3.0 x4 and SATA modes) storage devices support,6 x SATA 6Gb/s port(s),1 ...
Find elsewhere
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Tom's Hardware Forum
forums.tomshardware.com › home › motherboards
Question - Asus Prime X570 Pro, M.2 SSD Install questions! Pls HALP! | Tom's Hardware Forum
October 14, 2023 - Click to expand... Two drives, two ports, one heatsink. Various temperatures and speeds resulting. Operating system and data in various locations. That's a bunch of different permutations. You could try them all if you want. Experimentation over days or weeks.
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Tom's Hardware Forum
forums.tomshardware.com › home › storage
[SOLVED] - 2nd m.2 nvme on asus x570 pro mobo | Tom's Hardware Forum
December 16, 2021 - Hi, I have a decent build with a 3070, 5600x on an asus prime x570 pro. For boot drive, have an 1TB inland for os and such and has worked fine, gen pcie 3.0. It's full, so I'm looking to add a 2nd m.2 to the 2nd m.2 slot on the board. This will work of chipset and use some of the lanes. As...
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PC Gamer Forums
forums.pcgamer.com › home › computer hardware › desktop hardware
2nd m.2 slot on asus x570 pro adivice. | PC Gamer Forums
December 16, 2021 - Hi, I have a decent build with a 3070, 5600x on an asus prime x570 pro. For boot drive, have an 1TB inland for os and such and has worked fine, gen pcie 3.0. It's full, so I'm looking to add a 2nd m.2 to the 2nd m.2 slot on the board. This will work of chipset and use some of the lanes.
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ASUS
asus.com › motherboards / components › motherboards › csm › prime x570-p/csm
PRIME X570-P/CSM|Motherboards|ASUS Global
With PCIe 4.0 M.2 Slot supports up to 22110 and provide NVMe SSD RAID support for an incredible performance boost.
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Reddit
reddit.com › r › buildapc › comments › ifda4z › asus_prime_x570p_m2_x2_sata_pcie_40_bandwidth
r/buildapc - Asus prime x570-p - M.2 x2 + SATA + PCI-E 4.0? Bandwidth Allocation
January 24, 2021 -

Hello, I looked through the motherboard's manual but I couldn't find anything about the bandwidth allocation when using the M.2 slots together with SATA ports and PCI-E slots. I would like to buy a M.2 SSD while using a single GPU and 5 out of the 6 SATA ports, and most definitely will buy another M.2 SSD in the future and so would like to know how the bandwidth allocation works on this motherboard. Any help would be really appreciated!

It does mention how the two x16 pci-e slots work when using one or two GPUs but nothing about M.2/SATA. I don't fully understand how the bandwidth allocation works, but I have seen videos talking about how some slots get disabled or run slower when other slots/ports are occupied.

(Oh and I got a X3700 btw. Also a quick question about BIOS update, should I do it? PC works fine without an update so don't really wanna risk it if it won't give a noticeable performance difference)

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B&H Photo Video
bhphotovideo.com › bh photo
ASUS PRIME X570-P AM4 ATX Motherboard PRIME X570-P B&H Photo
ASUS PRIME X570-P AM4 ATX Motherboard
The ASUS PRIME X570-P AM4 ATX Motherboard is built on the AMD X570 chipset supporting second- and third-generation AMD Ryzen processors with an AM4 socket. It has four memory slots for up to 128GB of dual-channel DDR4 RAM, which can reach up to 4400 MHz when overclocked. For storage, it's equipped with six SATA III ports and two M.2 slots. There are two PCIe 4.0 x16 slots for graphics cards and a three PCIe 4.0 x1 slots for other PCI-based hardware. Other integrated features include an HDMI port, Realtek RTL8111H Gigabit LAN, and Realtek S1200A 8-channel HD audio.
Price   $159.99
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Asus
asus.com › motherboards / components › motherboards › asus prime motherboards › prime x570-pro
PRIME X570-PRO - Tech Specs|Motherboards|ASUS USA
Detailed specification of PRIME ... Max Memory Size:128GB、Graphics:1 x DisplayPort 1.2、Graphics:1 x DisplayPort 1.2、Storage:Supports 2 x M.2 slots and 6 x SATA 6Gb/s ports、Stor...
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Reddit
reddit.com › r/asus › prime x570-pro nvme question
r/ASUS on Reddit: Prime X570-Pro NVME question
January 9, 2020 -

So quick question, long time computer user , first time computer builder!

I have the Asus Prime X570-Pro (like it says in the title) and it has two M.2 slots. the lower one has a heatsink, the upper does not. I know generally the rule of thumb is to place the NVME in the upper slot but since the lower has a heatsink will the lower work for a NVME installed for my OS?

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Reddit
reddit.com › r/pcbuild › can i put 2 ssd cards in this motherboard? asus prime x570-p
r/PcBuild on Reddit: Can I put 2 SSD cards in this motherboard? Asus PRIME X570-P
September 13, 2023 - Oooh right, sorry. The NVMe slots are even harder to find! I found one hiding behind a case fan once, very sneaky! ... As other people have said, yes. If you want more than 2, you can find daughter pci-e cards, with more m.2 slots
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PCPartPicker
pcpartpicker.com › forums › topic › 406031-2nd-m2-slot-in-asus-pro-x570-pro
2nd m.2 slot in asus pro x570 pro - PCPartPicker
Hi, I have a decent build with a 3070, 5600x on an asus prime x570 pro. For boot drive, have an 1TB inland for os and such and has worked fine, gen pcie 3.0. It's full, so I'm looking to add a 2nd m.2 to the 2nd m.2 slot on the board. This will work of chipset and use some of the lanes.
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B&H Photo Video
bhphotovideo.com › lit_files › 589696.pdf pdf
Motherboard PRIME X570-P
cause you physical injury and damage motherboard components. Slot No. Slot Description · 1 · PCIe 4.0 x1_1 slot · 2 · PCIe 4.0/3.0 x16_1 slot · 3 · PCIe 4.0 x16_2 slot · 4 · PCIe 4.0 x1_2 slot · 5 · PCIe 4.0 x1_3 slot · PCIEX1_1 · PCIEX1_2 · PCIEX1_3 · PCIEX16_1 · PCIEX16_2 · ...
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Amazon
amazon.com › Asus-Prime-X570-P-Ryzen-Motherboard › dp › B07SW925DR
Amazon.com: Asus Prime X570-Pro AM4 Zen 3 Ryzen 5000 & 3rd Gen Ryzen ATX Motherboard with PCIe Gen4, Dual M.2 HDMI, SATA 6GB/s USB 3.2 Gen 2 : Electronics
PCIe 4.0 provides twice the bandwidth for data flowing through the chipset, which creates more heat than the previous generation. The Prime X570-P features an actively cooled heatsink to prevent throttling during sustained transfers. With PCIe 4.0 M.2 Slot supports up to 22110 and provide NVMe ...