The fastest native solution seems to be Win + Tab and then middle-click the Apps to close them.

The best 3rd party solution I found is 7+ Taskbar Tweaker. You can configure it to close Tasks by middle-click to the tasks entry immediately in the task bar. Unfortunately, Taskbar Tweaker seems to be tailor-fit very closely to Windows and broke with every major update (Anniversary, Creator). The maintainer each time fixed it within some weeks, but meanwhile everything defaults to the old behavior of opening new instances instead of closing old ones.

Answer from Sascha on Stack Exchange
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The Windows Club
thewindowsclub.com › the windows club › how to close running apps on windows 11
How to close running Apps on Windows 11
July 7, 2025 - Another easy method to close a running application is to use the keyboard shortcut key. You can press the ALT+F4 key combination to quickly close an app.
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Digital Citizen
digitalcitizen.life › close-apps-windows-10
8 ways to close apps in Windows 10 like a Pro | Digital Citizen
October 5, 2025 - This works in Windows 10's desktop and Tablet mode. Press the Ctrl, Alt, and Tab keys simultaneously In the Task switcher, you can see previews of all the open windows of your active apps.
Discussions

How can I gracefully close all open apps except Explorer with one click or keystroke?
How "gracefully" are you talking? There are multiple ways to close a program. The batch file/PowerShell method might be graceful or not, depending on exactly which commands you used. One option is to forcefully terminate each process/process group before shut down. There are also commands to gracefully ask a program to terminate. Generally it's the same command (taskkill/Stop-Process), without the /f/-force parameter. You can also interact with the program's GUI to close it, eg. using Alt+F4 keyboard shortcut,or clicking the X button in the top right (if there is one), or using File->Close in the menu bar (if it has one), or right-clicking the program icon in the taskbar and selecting Close Window. Applications may respond differently between graceful requests to terminate from the OS, and the GUI options to close. For example you mentioned Chrome, where the behaviour to automatically reopen tabs only occurs if the GUI is used to close the browser (and the option to automatically restore tabs is set), but not if you forcefully close it via command line (taskkill /f /IM chrome.exe). However it will restore tabs if you do it gracefully (taskkill /IM chrome.exe). Not all programs will necessarily behave the same way, however both Chrome and Word do.If you want to ensure you get the desired behaviour, the only reliable way to reproduce a GUI close is to use automation tools to simulate the same GUI interaction. You mentioned AutoHotKey in another comment, and yes that's one solution to achieve this. The problem is, if you want to automate this GUI interaction you also need to handle scenarios where the program refuses to close. Like in Word or Notepad, if you have an unsaved document, the GUI methods will prompt the user to save changes first. Each program will behave differently, so you'll need to account for every app you might possibly have open, and the different behaviours it might have to different states. At that point you either have an overly complicated automation, or you only have partial automation with user intervention required to handle any exceptions. Or you just accept the fact that terminating gracefully via command line is the easiest solution, even if some applications might not handle it the way you want. If you're willing to dig deeper, you might be interested in ARSO. But it'll only work with applications that explicitly support it, and I don't know of any way to trigger it manually. More on reddit.com
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June 20, 2024
Is there a Windows 10 shortcut to force quit apps? (for programs that prevent Alt+F4)
With the HotkeyP, you can create any shortcut to kill the active program/window, use the command "Terminate process". HotkeyP - keyboard/mouse/gamepad mapper (AutoHotkey alternative - but much easier to use, lightweight, many features, e.g. macros, hide window, opacity, change wallpaper, magnifier, volume, mute, disable key - like CapsLock...) More on reddit.com
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Is there a way to force close an app in windows
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March 26, 2024
How to close all background programs in Windows?
It becomes so bad that you have to buy a whole new computer. Why would you have to buy a new computer when you can simply clean install? More on reddit.com
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August 20, 2022
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Verificient
verificient.freshdesk.com › support › solutions › articles › 1000325125-ways-to-force-quit-apps-or-programs-on-a-windows-pc
Ways to force quit apps or programs on a Windows PC : Support
To quickly force quit on Windows, use the keyboard shortcut Alt + F4. You can also force quit on Windows by using Task Manager or Command Prompt. If these methods don't work, try restarting your computer. How to force quit on Windows usin...
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HelloTech
hellotech.com › home › how to force quit an app on a windows 10 pc
How To Force Quit an App on a Windows 10 PC : HelloTech How
January 25, 2024 - You have to select the application, so your computer knows that that’s the one you’re trying to close. Next, press the Alt + F4 keys at the same time. The F4 key is at the top of your keyboard, while the Alt key is to the left of most keyboards.
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Reddit
reddit.com › r/techsupport › how can i gracefully close all open apps except explorer with one click or keystroke?
r/techsupport on Reddit: How can I gracefully close all open apps except Explorer with one click or keystroke?
June 20, 2024 -

I'm doing some testing and frequently need to gracefully close all open apps either before running a program or rebooting. The batch file and PowerShell methods I've tried shut down chrome improperly, so I need to restore all open tabs. I want to simulate closing the app manually.

The main apps I typically have open are Chrome, Word, Titan Mail, Thunderbird, an image management program, Photoshop, possibly other Office or Adobe programs, and Notepad.

Top answer
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How "gracefully" are you talking? There are multiple ways to close a program. The batch file/PowerShell method might be graceful or not, depending on exactly which commands you used. One option is to forcefully terminate each process/process group before shut down. There are also commands to gracefully ask a program to terminate. Generally it's the same command (taskkill/Stop-Process), without the /f/-force parameter. You can also interact with the program's GUI to close it, eg. using Alt+F4 keyboard shortcut,or clicking the X button in the top right (if there is one), or using File->Close in the menu bar (if it has one), or right-clicking the program icon in the taskbar and selecting Close Window. Applications may respond differently between graceful requests to terminate from the OS, and the GUI options to close. For example you mentioned Chrome, where the behaviour to automatically reopen tabs only occurs if the GUI is used to close the browser (and the option to automatically restore tabs is set), but not if you forcefully close it via command line (taskkill /f /IM chrome.exe). However it will restore tabs if you do it gracefully (taskkill /IM chrome.exe). Not all programs will necessarily behave the same way, however both Chrome and Word do.If you want to ensure you get the desired behaviour, the only reliable way to reproduce a GUI close is to use automation tools to simulate the same GUI interaction. You mentioned AutoHotKey in another comment, and yes that's one solution to achieve this. The problem is, if you want to automate this GUI interaction you also need to handle scenarios where the program refuses to close. Like in Word or Notepad, if you have an unsaved document, the GUI methods will prompt the user to save changes first. Each program will behave differently, so you'll need to account for every app you might possibly have open, and the different behaviours it might have to different states. At that point you either have an overly complicated automation, or you only have partial automation with user intervention required to handle any exceptions. Or you just accept the fact that terminating gracefully via command line is the easiest solution, even if some applications might not handle it the way you want. If you're willing to dig deeper, you might be interested in ARSO. But it'll only work with applications that explicitly support it, and I don't know of any way to trigger it manually.
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You can't do it gracefully... Curiosity why/what makes you need this?
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Business Insider
businessinsider.com › business insider › 3 ways to force quit apps or programs on a windows pc
How to Force Quit Apps or Programs on Windows
December 7, 2022 - To quickly force quit on Windows, use the keyboard shortcut Alt + F4. You can also force quit on Windows by using Task Manager or Command Prompt. If these methods don't work, try restarting your computer.
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MakeUseOf
makeuseof.com › home › windows › 8 different ways to close apps and programs on windows
8 Different Ways to Close Apps and Programs on Windows
December 25, 2022 - Right-click on the title bar of the app window, and select Close from the context menu that appears. You can also press Alt + Spacebar to access the title bar menu and then press the C key on your keyboard to close the app window.
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CCleaner
ccleaner.com › knowledge › 5-ways-to-force-quit-any-frozen-app-on-windows
How to force quit on a Windows PC — CCleaner
Learn how to force quit on a Windows PC whether you're dealing with a frozen program or an unresponsive computer using various methods.
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Ascendant USA
ascendantusa.com › 2024 › 12 › 23 › force-quit-apps-on-windows
How to Force Quit Apps on Windows | Ascendant
December 30, 2025 - F4 keyboard combination is a straightforward and commonly recognized technique for forcefully exiting an application. To execute this action, you must maintain holding down the ‘Alt’ key while tapping ‘F4’. This process shines when you ...
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Reddit
reddit.com › r/windows › is there a windows 10 shortcut to force quit apps? (for programs that prevent alt+f4)
r/windows on Reddit: Is there a Windows 10 shortcut to force quit apps? (for programs that prevent Alt+F4)
November 4, 2019 - What I end up doing sometimes when the program won't close nor minimize is use Ctrl+Shift+Esc, see which program is selected in it through the Alt+Tab thumbnail, and use the arrow keys to navigate and kill the program.
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Digacore
digacore.com › blog › force-quit-windows-close-frozen-apps
Force Quit Windows: Easy Ways To Close Frozen Apps In 2025
October 29, 2025 - The process is safe when used right, ... these clear steps to stop a non-responsive app right away: Open Task Manager Press Ctrl + Shift + Esc on your keyboard....
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How-To Geek
howtogeek.com › home › windows › how to force quit an app on windows 10
How to Force Quit an App on Windows 10
February 6, 2024 - To open Task Manager, you can press Ctrl+Shift+Esc on your keyboard or right-click the Windows task bar and select “Task Manager” from the menu. With Task Manager open, select the task you want to force quit and then select “End Task.” ...
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Support Your Tech
supportyourtech.com › home › articles › how to close apps on windows 10: a step-by-step guide for users
How to Close Apps on Windows 10: A Step-by-Step Guide for Users
September 10, 2024 - If the app has unsaved work, it might prompt you to save before closing. Press the Alt key and the F4 key simultaneously while the app is active. This keyboard shortcut is a quick way to close the current app.
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Quora
quora.com › How-do-I-close-apps-in-Windows-10
How to close apps in Windows 10 - Quora
Answer (1 of 4): Method 1 of 2:Closing Apps in Regular (Desktop) Mode 1. Use the ✕ button window control. Move your mouse to the top-right. Be sure to hover over the ✕ button.
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ZDNET
zdnet.com › home › tech › services & software › operating systems › windows
How to force-quit applications in Windows | ZDNET
May 14, 2024 - In Windows 10 or 11, right-click the Start button and select Task Manager from the menu or press Ctrl+Shift+Esc. If Task Manager opens in compact view, you can click the button for More details to see the full view.
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Support Your Tech
supportyourtech.com › home › articles › how to close all apps on windows 10: a step-by-step guide
How to Close All Apps on Windows 10: A Step-by-Step Guide
September 16, 2024 - This tab shows all the running applications and background processes. You’ll find it easy to identify which apps are consuming your resources. Hold down the Ctrl key and click on each application you want to close.
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The Verge
theverge.com › how to › tech › microsoft
How to force quit an app in Windows | The Verge
October 14, 2022 - Press Alt + F4 (and maybe also Fn, depending on how your Function row is programmed). This will close whatever application you currently have selected.