Try this:

lst = [("aaaa8"),("bb8"),("ccc8"),("dddddd8")]
print([s.strip('8') for s in lst]) # remove the 8 from the string borders
print([s.replace('8', '') for s in lst]) # remove all the 8s 

The problem with your code right now is that you are trying to strip the list, not the attribute in the list. I encourage you to do more research on for loops. In the future, search on google, look at documentation, or look for other similar questions before asking your own.

The split method for strings is used for removing characters from the front and the rear of the string. In this situation, you want to remove specific characters from the middle of the string. To do this, we will use the string.replace(characterstoreplace, whattoreplaceitwith) method.

The resulting code should look like this. Please try to understand it for yourself rather than just copy pasting it. You can ask me if you have any questions.

lst1 = ['ZINC1_out.pdbqt', 'ZINC2_out.pdbqt', 'ZINC3_out.pdbqt']    

for i in range(len(lst1)): #goes through every attribute in the list, represented by i
        lst1[i] = lst1[i].replace("_out", "") #replaces '_out' with nothing and sets the new value

If you're using python2 and your inputs are strings (not unicodes), the absolutely best method is str.translate:

>>> chars_to_remove = ['.', '!', '?']
>>> subj = 'A.B!C?'
>>> subj.translate(None, ''.join(chars_to_remove))
'ABC'

Otherwise, there are following options to consider:

A. Iterate the subject char by char, omit unwanted characters and join the resulting list:

>>> sc = set(chars_to_remove)
>>> ''.join([c for c in subj if c not in sc])
'ABC'

(Note that the generator version ''.join(c for c ...) will be less efficient).

B. Create a regular expression on the fly and re.sub with an empty string:

>>> import re
>>> rx = '[' + re.escape(''.join(chars_to_remove)) + ']'
>>> re.sub(rx, '', subj)
'ABC'

(re.escape ensures that characters like ^ or ] won't break the regular expression).

C. Use the mapping variant of translate:

>>> chars_to_remove = [u'δ', u'Γ', u'ж']
>>> subj = u'AжBδCΓ'
>>> dd = {ord(c):None for c in chars_to_remove}
>>> subj.translate(dd)
u'ABC'

Full testing code and timings:

#coding=utf8

import re

def remove_chars_iter(subj, chars):
    sc = set(chars)
    return ''.join([c for c in subj if c not in sc])

def remove_chars_re(subj, chars):
    return re.sub('[' + re.escape(''.join(chars)) + ']', '', subj)

def remove_chars_re_unicode(subj, chars):
    return re.sub(u'(?u)[' + re.escape(''.join(chars)) + ']', '', subj)

def remove_chars_translate_bytes(subj, chars):
    return subj.translate(None, ''.join(chars))

def remove_chars_translate_unicode(subj, chars):
    d = {ord(c):None for c in chars}
    return subj.translate(d)

import timeit, sys

def profile(f):
    assert f(subj, chars_to_remove) == test
    t = timeit.timeit(lambda: f(subj, chars_to_remove), number=1000)
    print ('{0:.3f} {1}'.format(t, f.__name__))

print (sys.version)
PYTHON2 = sys.version_info[0] == 2

print ('\n"plain" string:\n')

chars_to_remove = ['.', '!', '?']
subj = 'A.B!C?' * 1000
test = 'ABC' * 1000

profile(remove_chars_iter)
profile(remove_chars_re)

if PYTHON2:
    profile(remove_chars_translate_bytes)
else:
    profile(remove_chars_translate_unicode)

print ('\nunicode string:\n')

if PYTHON2:
    chars_to_remove = [u'δ', u'Γ', u'ж']
    subj = u'AжBδCΓ'
else:
    chars_to_remove = ['δ', 'Γ', 'ж']
    subj = 'AжBδCΓ'

subj = subj * 1000
test = 'ABC' * 1000

profile(remove_chars_iter)

if PYTHON2:
    profile(remove_chars_re_unicode)
else:
    profile(remove_chars_re)

profile(remove_chars_translate_unicode)

Results:

2.7.5 (default, Mar  9 2014, 22:15:05) 
[GCC 4.2.1 Compatible Apple LLVM 5.0 (clang-500.0.68)]

"plain" string:

0.637 remove_chars_iter
0.649 remove_chars_re
0.010 remove_chars_translate_bytes

unicode string:

0.866 remove_chars_iter
0.680 remove_chars_re_unicode
1.373 remove_chars_translate_unicode

---

3.4.2 (v3.4.2:ab2c023a9432, Oct  5 2014, 20:42:22) 
[GCC 4.2.1 (Apple Inc. build 5666) (dot 3)]

"plain" string:

0.512 remove_chars_iter
0.574 remove_chars_re
0.765 remove_chars_translate_unicode

unicode string:

0.817 remove_chars_iter
0.686 remove_chars_re
0.876 remove_chars_translate_unicode

(As a side note, the figure for remove_chars_translate_bytes might give us a clue why the industry was reluctant to adopt Unicode for such a long time).

>>> re.findall(r'\{(.*)\}', '1:{test}')
['test']

Just make a loop with it:

[(re.findall(r'\{(.*)\}', i) or [''])[0] for i in your_list]

or maybe:

[''.join(re.findall(r'\{(.*)\}', i)) for i in your_list]