UCLA Health
uclahealth.org › medical-services › surgery › endocrine-surgery › patient-resources › patient-education › endocrine-surgery-encyclopedia › hypothyroidism-secondary
Hypothyroidism Secondary - Endocrine Surgery | UCLA Health
Thyroid disorders caused by ... hypothyroidism. The cause of secondary hypothyroidism is failure of the pituitary gland to secrete thyroid stimulating hormone (TSH)....
Verywell Health
verywellhealth.com › secondary-hypothyroidism-5272471
Secondary Hypothyroidism: Causes, Symptoms, Treatment
October 16, 2025 - Anatomical differences, or disorders of the pituitary gland and/or hypothalamus (a part of the brain that regulators numerous body functions), are associated with secondary hypothyroidism.
Videos
Hypothyroidism | Clinical Medicine - YouTube
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Hypothyroidism: A Diagnostic Approach - YouTube
05:40
Hypothyroidism and Hashimoto's Thyroiditis: Visual Explanation ...
Video: Hypothyroidism - Video Explanation! | Osmosis | Osmosis
04:26
Hypothyroidism (Underactive Thyroid): Symptoms, Diagnosis & Treatment ...
02:26
Signs of Hypothyroidism | UCLA Endocrine Center - YouTube
Just diagnosed with secondary hypothyroidism..anyone else?
What are your labs? I believe initially I was diagnosed with this, as my TSH was normal, but somewhere along the way that diagnosis got changed.
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February 5, 2023secondary hypothyroidism diagnosis! anyone experience some of these symptoms?
I have secondary/central hypothyroidism. Congratulations on a good endocrinologist! That's a great start.
I was also originally started on 50mcg, and while it helped, I wound up eventually going up to 100mcg.
Your symptoms could definitely be related to the lack of t4 in your system. Hopefully the meds will help resolve some of them quickly. (I remember feeling like my whole head was swollen.)
You could also be suffering from deficiencies. People with hypothyroidism tend to have trouble metabolizing and absorbing nutrients. Make sure your ferritin is well above 30. (Aim for 100) and your vitamin D is at the top of normal range.
Hopefully, your doctor also double checked ACTH and cortisol. Those could be low for us, and we need to be careful with levothyroxine if that's the case. (Edit: I see that was checked. Since it was a little low, keep an eye on that. Make sure to know the signs of an adrenal crisis just in case.)
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September 10, 2023FINALLY A DIAGNOSIS!! Central Hypothyroidism.
Just curious, has your doctor tested your ACTH and cortisol? I had similar thyroid levels (and thankfully, also a doctor who was willing to treat me - now I've got my life back!). My cortisol and ACTH are likewise unexpectedly off. Good luck to you! Hope you feel better soon :) More on reddit.com
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February 10, 2023Anyone have experience with Central (Secondary) Hypothyroidism? I just got my diagnosis.
Yes, I have Central Hypothyroidism after a Pituitary tumor removal. I've had this condition for over 14 1/2 years. When correcting the Central Hypothyroidism, your fT3 and fT4 levels are what should be looked at. In my case, my TSH is non-existent, so it's useless for determining how my thyroid meds are working. With Central Hypothyroidism, your fT3 and fT4 levels must be in the UPPER HALF of the range. Just being in range isn't good enough and you will still be Hypothyroid. If both fT3 and fT4 are low, you need to replace with Synthroid(Levothyroxine), which replaces fT4 and Cytomel(Liothyronine), which replaces fT3. Best Wishes! More on reddit.com
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April 20, 2022Merck Manual
merckmanuals.com › professional › endocrine and metabolic disorders › thyroid disorders › hypothyroidism
Hypothyroidism - Endocrine and Metabolic Disorders - Merck Manual Professional Edition
June 5, 2024 - The most common etiology of ... to the neck, or some medications). Secondary hypothyroidism is caused by hypothalamic or pituitary disease....
Endocrinologyadvisor
endocrinologyadvisor.com › home › ddi › central hypothyroidism
Central Hypothyroidism - Endocrinology Advisor
August 13, 2025 - Hypothyroidism may be defined as primary, secondary, or tertiary hypothyroidism. Primary hypothyroidism occurs when the thyroid gland does not produce enough thyroid hormone. Lack of iodine and Hashimoto thyroiditis are the 2 main causes of primary hypothyroidism.1 Secondary and tertiary hypothyroidism are also known as central hypothyroidism (CeH).
NCBI
ncbi.nlm.nih.gov › books › NBK519536
Hypothyroidism - StatPearls - NCBI Bookshelf
February 18, 2024 - The less commonly seen secondary or central hypothyroidism occurs when the thyroid gland functions normally; however, hypothyroidism results from the abnormal pituitary gland or hypothalamus function. Autoimmune thyroiditis and iodine deficiency are the most common causes of the disease.
Healthline
healthline.com › health › hypothryroidism › pituitary-hypothyroidism
Pituitary Hypothyroidism: Causes, Symptoms, and Treatment
March 23, 2023 - Secondary hypothyroidism is a rare form of hypothyroidism caused by your pituitary gland underproducing TSH.
Ucsf
ccpd.ucsf.edu › pituitary-disorders › hormonal-conditions › hypothyroidism
Hypothyroidism | California Center for Pituitary Disorders
Secondary (or central) hypothyroidism is caused by disorders of the pituitary gland or hypothalamus. Generally, secondary hypothyroidism is associated with low TSH and low T3 and T4. However, TSH levels may also be normal or even slightly elevated.
Johns Hopkins Medicine
hopkinsmedicine.org › health › conditions-and-diseases › hypothyroidism
Hypothyroidism | Johns Hopkins Medicine
The normal thyroid cells are overrun by white blood cells and scar tissue. Another cause may be treatment for an overactive thyroid gland. That may include radioactive iodine therapy or surgery. Hypothyroidism may also develop shortly after pregnancy. A condition called secondary hypothyroidism ...
ScienceDirect
sciencedirect.com › science › article › pii › S221462371830067X
Less known aspects of central hypothyroidism: Part 1 – Acquired etiologies - ScienceDirect
September 26, 2018 - Central hypothyroidism (CH) is a rare cause of hypothyroidism. CH is frequently overlooked, as its clinical picture is subtle and includes non-specifi…
Mayo Clinic
mayoclinic.org › diseases-conditions › hypothyroidism › symptoms-causes › syc-20350284
Hypothyroidism (underactive thyroid) - Symptoms and causes - Mayo Clinic
December 10, 2022 - Understand what happens when your thyroid is underactive and learn about treatment for this condition.
Zero To Finals
zerotofinals.com › medicine › endocrinology › hypothyroidism
Hypothyroidism – Zero To Finals
Secondary hypothyroidism, also called central hypothyroidism, is where the pituitary behaves abnormally and produces inadequate TSH, resulting in under-stimulation of the thyroid gland and insufficient thyroid hormones. TSH, T3 and T4 will all be low. Hashimoto’s thyroiditis is the most common cause of hypothyroidism in the developed world.
Paloma Health
palomahealth.com › learn › secondary-hypothyroidism
What Is Secondary Hypothyroidism? | Paloma Health
September 25, 2024 - TSH is the pituitary’s messenger hormone, communicating to the thyroid gland to ramp up or slow down thyroid hormone production. Several factors can cause secondary hypothyroidism, but a pituitary tumor is the most common cause.
American Academy of Family Physicians
aafp.org › pubs › afp › issues › 2012 › 0801 › p244.html
Hypothyroidism: An Update | AAFP
August 1, 2012 - Autoimmune thyroid disease is the most common etiology of hypothyroidism in the United States.4 Iatrogenic forms of hypothyroidism occur after thyroid surgery, radioiodine therapy, and neck irradiation.5 Disorders generally associated with transient ...
Texas Department of State Health Services
dshs.texas.gov › home › newborn screening program › newborn screening parent resources › secondary hypothyroidism
Secondary Hypothyroidism | Texas DSHS
The hypothalamus releases a hormone called thyrotropin (TRH), which sends a signal to the pituitary to release thyroid stimulating hormone (TSH). In turn, TSH sends a signal to the thyroid to release thyroid hormones (T4 and T3). If any of these hormone signals are interrupted, a defect in thyroid hormone production will result in a deficiency of thyroid hormone causing secondary hypothyroidism.
Mount Sinai
mountsinai.org › health-library › report › hypothyroidism
Hypothyroidism Information | Mount Sinai - New York
In rare instances, usually due to a tumor, the pituitary gland will fail to produce TSH, the hormone that stimulates the thyroid to produce its hormones. In such cases, the thyroid gland shrinks and secondary hypothyroidism occurs.
RACGP
racgp.org.au › afp › 2012 › august › hypothyroidism
RACGP - Hypothyroidism - Investigation and management
April 9, 2012 - AetiologyIodine deficiency remains the most common cause of hypothyroidism worldwide.4 However, in Australia and other iodine replete countries, autoimmune chronic…
MedlinePlus
medlineplus.gov › home › health topics
Hypothyroidism | Hashimoto's Disease | MedlinePlus
Hypothyroidism happens when your thyroid gland does not make enough thyroid hormone to meet your body's needs. Hypothyroidism is more common in women.
Better Health Channel
betterhealth.vic.gov.au › health › conditionsandtreatments › thyroid-hypothyroidism
Thyroid - hypothyroidism | Better Health Channel
Primary hypothyroidism means that the thyroid gland itself is diseased, while secondary hypothyroidism is caused by problems with the pituitary gland, the brain structure that supervises the thyroid gland.
Medscape
emedicine.medscape.com › tools & reference › endocrinology
Hypothyroidism: Background, Pathophysiology, Etiology
Hypothyroidism can also be secondary, a condition in which the thyroid gland itself is normal but receives insufficient stimulation because of low secretion of thyrotropin (ie, thyroid-stimulating hormone [TSH]) from the pituitary gland. This generally occurs in the presence of other pituitary ...
AMBOSS
amboss.com › us › knowledge › hypothyroidism
Hypothyroidism - Knowledge @ AMBOSS
2 weeks ago - Thyroid dysplasia: a disorder of embryologic development characterized by abnormal development and/or location of thyroid tissue (e.g., lingual thyroid) Secondary hypothyroidism: pituitary disorders (e.g., pituitary adenoma) → TSH deficiency