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Mayo Clinic
mayoclinic.org › diseases-conditions › hypothyroidism › symptoms-causes › syc-20350284
Hypothyroidism (underactive thyroid) - Symptoms and causes - Mayo Clinic
December 10, 2022 - Understand what happens when your thyroid is underactive and learn about treatment for this condition.
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NHS
nhs.uk › conditions › underactive-thyroid-hypothyroidism
Underactive thyroid (hypothyroidism) - NHS
In the UK, the main cause of an underactive thyroid is an autoimmune condition called Hashimoto's disease.
Discussions

What’s the root cause of low thyroid?
I’m sorry you are going through this. The answer to your question can be long; my class on this topic is about 40 minutes. But here’s the bullet point list. When I'm teaching, I cover the following root causes: Genetics (obviously you can't change that, but google "nutrigenomics.") Gut Triggers Hormone changes (puberty, pregnancy, perimenopause) and estrogen overload iodine low vitamin d food reactions environmental chemicals stress blood sugar issues (your not eating would fall into this category. Low blood sugar (fasting) tends to be a bigger stressor/trigger for Hashimoto’s than high blood sugar.) infections of any kind More on reddit.com
🌐 r/Hypothyroidism
42
5
June 15, 2023
Weird/lesser known symptoms?
Some odd symptoms I had when younger before diagnosis - depth perception issues - I would slam my shoulder into doorframes, or break my toes because I would stub them so often, peeling fingertips. Those things stopped once I became medicated. More on reddit.com
🌐 r/Hypothyroidism
268
98
December 7, 2023
Hypothyroidism: What are/were your symptoms ?

Weight gain, fatigue, nausea, dizziness, hypoglycemia, mood swings, depression, hair loss, dry skin, joint pain.

More on reddit.com
🌐 r/Hypothyroidism
133
74
August 26, 2017
What were the first symptoms you noticed?
All above symptoms, except the weight gain. I had brain fog, woke up in a confusing about what to do. Words would go away, could not recall everyday items and people. My boss made fu of me, knowing that I was suffering. I was terrified. My primary doctor refused to help. My psychiatrist just wanted to give ne anti depressants. I refused. Finally, my rumatoligist tested me for everything, 7 vials of blood. I am off water pills ,blood pressure medication and arthritis pills. More on reddit.com
🌐 r/Hypothyroidism
113
46
December 11, 2022
People also ask

Can stress cause hypothyroidism?
Stress can definitely contribute to hypothyroidism. Both stressful events and chronic stress can affect your thyroid hormone levels and worsen autoimmune thyroid disease. Reducing stress may help treat hypothyroidism and some of its symptoms. One study showed that managing stress helped lower anti-thyroglobulin antibodies in women with Hashimoto’s hypothyroidism.
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goodrx.com
goodrx.com › goodrx health › health conditions › hypothyroidism: symptoms, causes, and treatments › 8 causes of hypothyroidism (underactive thyroid)
8 Causes of Hypothyroidism (Underactive Thyroid) - GoodRx
What causes hypothyroidism in women?
In general, women are more likely than men to get hypothyroidism. The most common cause is Hashimoto’s disease. Other common causes include not getting enough iodine, temporary hypothyroidism from subacute thyroiditis, certain medications (like lithium), and thyroid surgery or radiation treatment.
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goodrx.com
goodrx.com › goodrx health › health conditions › hypothyroidism: symptoms, causes, and treatments › 8 causes of hypothyroidism (underactive thyroid)
8 Causes of Hypothyroidism (Underactive Thyroid) - GoodRx
What is the most common cause of hypothyroidism?
In the U.S., Hashimoto’s disease is the most common cause of hypothyroidism. In this autoimmune disease, your immune system attacks your thyroid. This causes inflammation and your thyroid can’t make enough thyroid hormone. In areas of the world where people don’t get enough iodine in their diet, low iodine intake is the most common cause of hypothyroidism.
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goodrx.com
goodrx.com › goodrx health › health conditions › hypothyroidism: symptoms, causes, and treatments › 8 causes of hypothyroidism (underactive thyroid)
8 Causes of Hypothyroidism (Underactive Thyroid) - GoodRx
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MedlinePlus
medlineplus.gov › home › health topics
Hypothyroidism | Hashimoto's Disease | MedlinePlus
Hypothyroidism, or underactive thyroid, happens when your thyroid gland doesn't make enough thyroid hormones to meet your body's needs.
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NIDDK
niddk.nih.gov › home › health information › endocrine diseases › hypothyroidism (underactive thyroid)
Hypothyroidism (Underactive Thyroid) - NIDDK
October 3, 2025 - Thyroiditis, an inflammation of your thyroid, causes stored thyroid hormone to leak out of your thyroid gland. At first, the leakage increases your blood’s hormone levels, leading to thyrotoxicosis, a condition in which thyroid hormone levels are too high. The thyrotoxicosis may last for many months. After that, your thyroid may become underactive and, over time, the condition may become permanent, requiring thyroid hormone replacement.
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GoodRx
goodrx.com › goodrx health › health conditions › hypothyroidism: symptoms, causes, and treatments › 8 causes of hypothyroidism (underactive thyroid)
8 Causes of Hypothyroidism (Underactive Thyroid) - GoodRx
April 24, 2025 - Medications, thyroiditis, and certain deficiencies can all cause hypothyroidism. Here we explore the most common causes of primary and secondary hypothyroidism.
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Penn Medicine
pennmedicine.org › home › conditions we treat › hypothyroidism
Hypothyroidism – Symptoms and Causes | Penn Medicine
1 month ago - The thyroid gland can become inflamed due to an autoimmune reaction, because of a viral or respiratory infection, or after pregnancy (postpartum thyroiditis). Other causes of an underactive thyroid include radiation therapy, certain medications like lithium, birth defects, a pituitary tumor, ...
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American Thyroid Association
thyroid.org › home › hypothyroidism
Hypothyroidism | American Thyroid Association
September 10, 2015 - Hypothyroidism happens when the thyroid doesn’t make enough hormones.
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NHS inform
nhsinform.scot › home › illnesses and conditions › glands › underactive thyroid
Underactive thyroid symptoms and treatments
February 10, 2025 - Most cases of an underactive thyroid are caused by the immune system attacking the thyroid gland and damaging it, or by damage that occurs as a result of treatments for thyroid cancer or an overactive thyroid.
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Johns Hopkins Medicine
hopkinsmedicine.org › health › conditions-and-diseases › hypothyroidism
Hypothyroidism | Johns Hopkins Medicine
Hypothyroidism means your thyroid gland is underactive. It isn’t making enough thyroid hormone. The most common cause is when your immune system starts to attack itself.
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UpToDate
uptodate.com › contents › disorders-that-cause-hypothyroidism
Disorders that cause hypothyroidism
UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide.
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Cleveland Clinic
my.clevelandclinic.org › health › diseases › 8541-thyroid-disease
Thyroid Disease: What It Is, Causes, Symptoms & Treatment
June 2, 2025 - Hashimoto’s disease: This is a lifelong (chronic) autoimmune condition that can cause an underactive thyroid.
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NCBI
ncbi.nlm.nih.gov › books › NBK279601
Overview: Underactive thyroid (hypothyroidism) - InformedHealth.org - NCBI Bookshelf
May 28, 2024 - This condition is also referred to as hypothyroidism. It can lead to various problems, such as tiredness, lethargy, changes in the skin, and constipation. Chronic inflammation of the thyroid gland (Hashimoto's disease) is the most common cause of an underactive thyroid.
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Harvard Health
health.harvard.edu › newsletter_article › the-lowdown-on-thyroid-slowdown
The lowdown on thyroid slowdown - Harvard Health
August 17, 2021 - Before writing them off as products of aging, it's a good idea to make sure they're not the result of an underactive thyroid. This tiny butterfly-shaped gland influences virtually every organ system in the body. The hormones it secretes into the bloodstream play a vital role in regulating metabolism — the rate at which our bodies convert food and oxygen to energy. Low thyroid hormone production, or hypothyroidism, causes a range of symptoms, such as fatigue, constipation, dry skin and brittle nails, aches and pains, and feeling down.
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Merck Manual
merckmanuals.com › home › hormonal and metabolic disorders › thyroid gland disorders › hypothyroidism
Hypothyroidism - Hormonal and Metabolic Disorders - Merck Manual Consumer Version
Hypothyroidism is underactivity of the thyroid gland that leads to inadequate production of thyroid hormones and a slowing of vital body functions.
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Better Health Channel
betterhealth.vic.gov.au › health › conditionsandtreatments › thyroid-hypothyroidism
Thyroid - hypothyroidism | Better Health Channel
Hypothyroidism means the thyroid gland is underactive and fails to secrete enough hormones into the bloodstream. Causes include the autoimmune condition Hashimotos disease and insufficient dietary iodine.
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HSE.ie
www2.hse.ie › conditions › underactive-thyroid-hypothyroidism › causes
Underactive thyroid (hypothyroidism) - Causes
A problem with the pituitary gland can lead to an underactive thyroid. The pituitary gland sits at the base of the brain. It regulates the thyroid. If it's damaged it may lead to an underactive thyroid. Some medicines may cause an underactive thyroid.
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WebMD
webmd.com › women's health › reference
Hypothyroidism (Underactive Thyroid): Symptoms, Causes, Tests, Treatments
January 13, 2025 - Secondary hypothyroidism occurs when another problem interferes with the thyroid's ability to produce hormones. For example, any problem with the pituitary gland or hypothalamus can make your thyroid underactive, as these glands produce hormones ...

human disease

Molecular structure of the thyroxine molecule
Hypothyroidism
Hypothyroidism
Photograph of a Labrador Retriever dog with sagging facial skin characteristic of hypothyroidism
signs and symptoms of hypothyroidism
Hypothyroidism is an endocrine disease in which the thyroid gland does not produce enough thyroid hormones. It can cause a number of symptoms, such as poor ability to tolerate cold, extreme fatigue, … Wikipedia
Factsheet
Hypothyroidism Molecular structure of thyroxine, which is deficient in hypothyroidism
Specialty Endocrinology
Factsheet
Hypothyroidism Molecular structure of thyroxine, which is deficient in hypothyroidism
Specialty Endocrinology
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Wikipedia
en.wikipedia.org › wiki › Hypothyroidism
Hypothyroidism - Wikipedia
2 days ago - Less common causes include previous treatment with radioactive iodine, injury to the hypothalamus or the anterior pituitary gland, certain medications, a lack of a functioning thyroid at birth, or previous thyroid surgery.
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HealthDirect
healthdirect.gov.au › hypothyroidism
Hypothyroidism (underactive thyroid) | healthdirect
December 17, 2024 - Hypothyroidism (also known as an underactive thyroid) is when your thyroid gland does not make enough thyroid hormone. Symptoms of hypothyroidism can include tiredness, weight gain, bloating or sensitivity to the cold. The most common cause of hypothyroidism in Australia is an autoimmune condition ...
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Healthline
healthline.com › health › hypothyroidism › symptoms-treatments-more
Hypothyroidism (Underactive Thyroid): Symptoms, Causes, Treatment
June 30, 2025 - Hashimoto’s thyroiditis is an autoimmune condition and the · most common cause of an underactive thyroid in the United States.